Matches in SemOpenAlex for { <https://semopenalex.org/work/W2023346014> ?p ?o ?g. }
- W2023346014 endingPage "7" @default.
- W2023346014 startingPage "1" @default.
- W2023346014 abstract "The present study investigated posttranslational reactions in the salivary glands of patients with Sjögren’s syndrome. We analysed the biopsies of primary Sjögren’s patients using immunohistochemistry and a tag-purified anticyclic citrullinated protein (CCP) antibody to detect citrullinated peptides, and the presence of peptidylarginine deiminase 2 (PAD2) was assessed simultaneously. The present work demonstrated the weak presence of the PAD2 enzyme in some normal salivary glands, although PAD2 expression was increased considerably in Sjögren’s patients. The presence of citrullinated proteins was also detected in the salivary tissues of Sjögren’s patients, which strongly supports the in situ posttranslational modification of proteins in this setting. Furthermore, the mutual expression of CCP and PAD2 suggests that this posttranslational modification is enzyme dependent. In conclusion, patients with Sjögren’s syndrome expressed the catalytic machinery to produce posttranslational reactions that may result in autoantigen triggering." @default.
- W2023346014 created "2016-06-24" @default.
- W2023346014 creator A5006281529 @default.
- W2023346014 creator A5010319858 @default.
- W2023346014 creator A5024917202 @default.
- W2023346014 creator A5064156111 @default.
- W2023346014 creator A5072851136 @default.
- W2023346014 creator A5075095455 @default.
- W2023346014 creator A5081962491 @default.
- W2023346014 creator A5085490201 @default.
- W2023346014 date "2013-01-01" @default.
- W2023346014 modified "2023-10-18" @default.
- W2023346014 title "Posttranslational Protein Modification in the Salivary Glands of Sjögren’s Syndrome Patients" @default.
- W2023346014 cites W1918768783 @default.
- W2023346014 cites W1971329568 @default.
- W2023346014 cites W1975891446 @default.
- W2023346014 cites W1980694300 @default.
- W2023346014 cites W2010651946 @default.
- W2023346014 cites W2015447263 @default.
- W2023346014 cites W2026788098 @default.
- W2023346014 cites W2034839671 @default.
- W2023346014 cites W2036104418 @default.
- W2023346014 cites W2038780641 @default.
- W2023346014 cites W2040113869 @default.
- W2023346014 cites W2067645583 @default.
- W2023346014 cites W2080726191 @default.
- W2023346014 cites W2082948543 @default.
- W2023346014 cites W2084043206 @default.
- W2023346014 cites W2092809155 @default.
- W2023346014 cites W2101735337 @default.
- W2023346014 cites W2106471468 @default.
- W2023346014 cites W2108595441 @default.
- W2023346014 cites W2109578241 @default.
- W2023346014 cites W2116286193 @default.
- W2023346014 cites W2138891799 @default.
- W2023346014 cites W2143033111 @default.
- W2023346014 cites W2154040419 @default.
- W2023346014 cites W2164300339 @default.
- W2023346014 cites W2167385753 @default.
- W2023346014 cites W2168831715 @default.
- W2023346014 cites W2170200755 @default.
- W2023346014 cites W2171800907 @default.
- W2023346014 cites W2432195370 @default.
- W2023346014 cites W4293247451 @default.
- W2023346014 doi "https://doi.org/10.1155/2013/548064" @default.
- W2023346014 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3603161" @default.
- W2023346014 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/23533719" @default.
- W2023346014 hasPublicationYear "2013" @default.
- W2023346014 type Work @default.
- W2023346014 sameAs 2023346014 @default.
- W2023346014 citedByCount "9" @default.
- W2023346014 countsByYear W20233460142016 @default.
- W2023346014 countsByYear W20233460142017 @default.
- W2023346014 countsByYear W20233460142023 @default.
- W2023346014 crossrefType "journal-article" @default.
- W2023346014 hasAuthorship W2023346014A5006281529 @default.
- W2023346014 hasAuthorship W2023346014A5010319858 @default.
- W2023346014 hasAuthorship W2023346014A5024917202 @default.
- W2023346014 hasAuthorship W2023346014A5064156111 @default.
- W2023346014 hasAuthorship W2023346014A5072851136 @default.
- W2023346014 hasAuthorship W2023346014A5075095455 @default.
- W2023346014 hasAuthorship W2023346014A5081962491 @default.
- W2023346014 hasAuthorship W2023346014A5085490201 @default.
- W2023346014 hasBestOaLocation W20233460141 @default.
- W2023346014 hasConcept C100631289 @default.
- W2023346014 hasConcept C142724271 @default.
- W2023346014 hasConcept C153911025 @default.
- W2023346014 hasConcept C159654299 @default.
- W2023346014 hasConcept C163764329 @default.
- W2023346014 hasConcept C181199279 @default.
- W2023346014 hasConcept C185592680 @default.
- W2023346014 hasConcept C203014093 @default.
- W2023346014 hasConcept C204232928 @default.
- W2023346014 hasConcept C2777468819 @default.
- W2023346014 hasConcept C2777706064 @default.
- W2023346014 hasConcept C2778937882 @default.
- W2023346014 hasConcept C2779075594 @default.
- W2023346014 hasConcept C2779129087 @default.
- W2023346014 hasConcept C48632299 @default.
- W2023346014 hasConcept C515207424 @default.
- W2023346014 hasConcept C55493867 @default.
- W2023346014 hasConcept C71924100 @default.
- W2023346014 hasConcept C86803240 @default.
- W2023346014 hasConceptScore W2023346014C100631289 @default.
- W2023346014 hasConceptScore W2023346014C142724271 @default.
- W2023346014 hasConceptScore W2023346014C153911025 @default.
- W2023346014 hasConceptScore W2023346014C159654299 @default.
- W2023346014 hasConceptScore W2023346014C163764329 @default.
- W2023346014 hasConceptScore W2023346014C181199279 @default.
- W2023346014 hasConceptScore W2023346014C185592680 @default.
- W2023346014 hasConceptScore W2023346014C203014093 @default.
- W2023346014 hasConceptScore W2023346014C204232928 @default.
- W2023346014 hasConceptScore W2023346014C2777468819 @default.
- W2023346014 hasConceptScore W2023346014C2777706064 @default.
- W2023346014 hasConceptScore W2023346014C2778937882 @default.
- W2023346014 hasConceptScore W2023346014C2779075594 @default.
- W2023346014 hasConceptScore W2023346014C2779129087 @default.
- W2023346014 hasConceptScore W2023346014C48632299 @default.