Matches in SemOpenAlex for { <https://semopenalex.org/work/W2023346148> ?p ?o ?g. }
Showing items 1 to 90 of
90
with 100 items per page.
- W2023346148 endingPage "485" @default.
- W2023346148 startingPage "479" @default.
- W2023346148 abstract "Normal synovial membranes and synovial membranes from patients with classic rheumatoid arthritis were investigated for the presence of fibrin and fibronectin by an indirect immunoperoxidase technique. In normal synovial membranes, fibronectin was found around the monolayer of the synovial lining cells. Staining was most intense on the surface and beneath the lining cells, but not detectable in the cytoplasm. Fibronectin was also found in the cytoplasm of the endothelial cells. No staining for fibrin was found in the normal synovial membrane. In synovial membranes from patients with rheumatoid arthritis, large amounts of fibronectin were found around the multilayer of synovial lining cells, in the cytoplasm of the endothelial cells, and in argyrophilic fiber-rich connective tissue. In superficial areas denuded of synovial lining cells, high amounts of fibronectin were found incorporated in fibrin. In some areas with noninjured synovial lining cells, fibrin was also found, but in this case no fibronectin was incorporated. No fibronectin was found in connective tissue in areas with infiltration of inflammatory cells. After treatment of normal and rheumatoid synovial membranes with hyaluronidase, fibronectin was still present around the lining cells but the staining was found to be more distinct. This study relates the presence of fibrin and fibronectin in the rheumatoid synovial membrane to the high amount of these proteins, recently described, in rheumatoid synovial fluid. It also suggests that fibronectin present in the synovial membrane is produced and secreted by the endothelial cells." @default.
- W2023346148 created "2016-06-24" @default.
- W2023346148 creator A5053216098 @default.
- W2023346148 creator A5071231365 @default.
- W2023346148 creator A5088058342 @default.
- W2023346148 date "1983-04-01" @default.
- W2023346148 modified "2023-10-18" @default.
- W2023346148 title "Fibrin and fibronectin in rheumatoid synovial membrane and rheumatoid synovial fluid" @default.
- W2023346148 cites W1506178395 @default.
- W2023346148 cites W1586370846 @default.
- W2023346148 cites W1988674295 @default.
- W2023346148 cites W1990477471 @default.
- W2023346148 cites W1993582348 @default.
- W2023346148 cites W2022315961 @default.
- W2023346148 cites W2078067897 @default.
- W2023346148 cites W2086593632 @default.
- W2023346148 cites W2095817939 @default.
- W2023346148 cites W2148041105 @default.
- W2023346148 cites W2266846107 @default.
- W2023346148 cites W4241369659 @default.
- W2023346148 cites W4250589130 @default.
- W2023346148 cites W4251824554 @default.
- W2023346148 cites W624888892 @default.
- W2023346148 doi "https://doi.org/10.1002/art.1780260405" @default.
- W2023346148 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/6340698" @default.
- W2023346148 hasPublicationYear "1983" @default.
- W2023346148 type Work @default.
- W2023346148 sameAs 2023346148 @default.
- W2023346148 citedByCount "74" @default.
- W2023346148 countsByYear W20233461482012 @default.
- W2023346148 countsByYear W20233461482013 @default.
- W2023346148 countsByYear W20233461482016 @default.
- W2023346148 countsByYear W20233461482017 @default.
- W2023346148 countsByYear W20233461482022 @default.
- W2023346148 crossrefType "journal-article" @default.
- W2023346148 hasAuthorship W2023346148A5053216098 @default.
- W2023346148 hasAuthorship W2023346148A5071231365 @default.
- W2023346148 hasAuthorship W2023346148A5088058342 @default.
- W2023346148 hasConcept C142724271 @default.
- W2023346148 hasConcept C1491633281 @default.
- W2023346148 hasConcept C185592680 @default.
- W2023346148 hasConcept C190062978 @default.
- W2023346148 hasConcept C203014093 @default.
- W2023346148 hasConcept C204787440 @default.
- W2023346148 hasConcept C2776164576 @default.
- W2023346148 hasConcept C2776268809 @default.
- W2023346148 hasConcept C2777575956 @default.
- W2023346148 hasConcept C2777652487 @default.
- W2023346148 hasConcept C518705261 @default.
- W2023346148 hasConcept C54173615 @default.
- W2023346148 hasConcept C55493867 @default.
- W2023346148 hasConcept C71924100 @default.
- W2023346148 hasConcept C86492073 @default.
- W2023346148 hasConceptScore W2023346148C142724271 @default.
- W2023346148 hasConceptScore W2023346148C1491633281 @default.
- W2023346148 hasConceptScore W2023346148C185592680 @default.
- W2023346148 hasConceptScore W2023346148C190062978 @default.
- W2023346148 hasConceptScore W2023346148C203014093 @default.
- W2023346148 hasConceptScore W2023346148C204787440 @default.
- W2023346148 hasConceptScore W2023346148C2776164576 @default.
- W2023346148 hasConceptScore W2023346148C2776268809 @default.
- W2023346148 hasConceptScore W2023346148C2777575956 @default.
- W2023346148 hasConceptScore W2023346148C2777652487 @default.
- W2023346148 hasConceptScore W2023346148C518705261 @default.
- W2023346148 hasConceptScore W2023346148C54173615 @default.
- W2023346148 hasConceptScore W2023346148C55493867 @default.
- W2023346148 hasConceptScore W2023346148C71924100 @default.
- W2023346148 hasConceptScore W2023346148C86492073 @default.
- W2023346148 hasIssue "4" @default.
- W2023346148 hasLocation W20233461481 @default.
- W2023346148 hasLocation W20233461482 @default.
- W2023346148 hasOpenAccess W2023346148 @default.
- W2023346148 hasPrimaryLocation W20233461481 @default.
- W2023346148 hasRelatedWork W1960988955 @default.
- W2023346148 hasRelatedWork W1975690515 @default.
- W2023346148 hasRelatedWork W2011384560 @default.
- W2023346148 hasRelatedWork W2064600176 @default.
- W2023346148 hasRelatedWork W2157304310 @default.
- W2023346148 hasRelatedWork W2284864965 @default.
- W2023346148 hasRelatedWork W2402473517 @default.
- W2023346148 hasRelatedWork W2415637903 @default.
- W2023346148 hasRelatedWork W2470623763 @default.
- W2023346148 hasRelatedWork W4214479130 @default.
- W2023346148 hasVolume "26" @default.
- W2023346148 isParatext "false" @default.
- W2023346148 isRetracted "false" @default.
- W2023346148 magId "2023346148" @default.
- W2023346148 workType "article" @default.