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• W2023348037 abstract "Recent studies in terrestrial animals have shown that feeding the oxidized lipids led to a reduction in triacylglycerols (TAG) and total cholesterol (TC) in liver and plasma. However, limited information is available on the effect of oxidized lipids on lipid metabolism in fish. In this study, four diets containing 0 g kg−1 (control: fresh fish oil), 30 g kg−1 (low-oxidized oil, LOO), 60 g kg−1 (medium-oxidized oil, MOO) and 90 g kg−1 (high-oxidized oil, HOO) graded oxidized oil levels with the same dietary lipid level were fed to channel catfish for 86 days. The tissue lipid metabolism and fatty acid composition of the fish were investigated after this period. The results showed that plasma and liver concentrations of TAG and TC decreased with increasing dietary oxidized oil level (P < 0.05). Decreasing liver lipoprotein lipase and hepatic lipase activities were observed with increasing dietary oxidized fish oil inclusion (P < 0.05). The liver C22:6n−3 concentrations significantly decreased with increasing dietary oxidized oil level (P < 0.05), while muscle lipid had a high proportion of polyunsaturated fatty acids. It suggests that the adverse effects of dietary oxidized oil may be induced by inhibiting lipid metabolism enzymes and, consequently, inhibition of cholesterol homoeostasis and fatty acid synthesis." @default.
• W2023348037 created "2016-06-24" @default.
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• W2023348037 date "2013-02-01" @default.
• W2023348037 modified "2023-10-16" @default.
• W2023348037 title "Effects of oxidized fish oil intake on tissue lipid metabolism and fatty acid composition of channel catfish (<i>Ictalurus punctatus</i>)" @default.
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• W2023348037 doi "https://doi.org/10.1111/are.12138" @default.
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