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- W2023349831 abstract "The B subunit of cholera toxin, which is multivalent and binds exclusively to a specific ganglioside, GM1, was mitogenic for rat thymocytes. When exposed to the B subunit, the cells proliferated, as measured by 3H-labeled thymidine incorporation. Mitogenesis depended on the direct interaction of the B subunit with GM1 on the surface of the cells. This demonstrates that endogenous plasma membrane gangliosides can mediate proliferation in lymphocytes." @default.
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- W2023349831 date "1985-12-13" @default.
- W2023349831 modified "2023-09-25" @default.
- W2023349831 title "Direct Evidence That Endogenous G <sub>M1</sub> Ganglioside Can Mediate Thymocyte Proliferation" @default.
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- W2023349831 doi "https://doi.org/10.1126/science.2999979" @default.
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