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- W2023351923 abstract "A new enzyme, which we named ribosome RNA apurinic site specific lyase (RALyase), has been characterized. The enzyme specifically cleaves a phosphodiester bond at the apurinic site in the sarcin/ricin domain of 28S rRNA in ribosomes. The cut ends of wheat 28S rRNA were determined as 5'---GUACG-alpha-hydroxy-alpha, beta-unsaturated aldehyde and pGAGGA---3' for the 3' fragment, demonstrating that the enzyme catalyzes the beta-elimination reaction." @default.
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- W2023351923 date "1999-11-01" @default.
- W2023351923 modified "2023-09-25" @default.
- W2023351923 title "Mechanism of ribosome RNA apurinic site specific lyase" @default.
- W2023351923 doi "https://doi.org/10.1093/nass/42.1.257" @default.
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