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- W2023353731 abstract "The effect of caerulein, an analog of cholecystokinin-8, on expression of the immediate-early genes c-fos and zif/268 was studied in the rat brain using Northern blot analysis and an in situ hybridization technique. Intraperitoneal injection of caerulein did not change the basal c-fos and zif/268 expression. Administration of the convulsant, pentylenetetrazole (PTZ), caused a dramatic increase of c-fos and zif/268 mRNAs in the hippocampus and dentate gyrus. Pretreatment with caerulein suppressed the PTZ-induced c-fos and zif/268 expression. It is considered that systemically administrated caerulein modifies neuronal activities by exerting a suppressed effect on induction of the immediate-early genes." @default.
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- W2023353731 date "1992-10-01" @default.
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- W2023353731 title "Effect of caerulein on expression of the immediate-early genes c-fos and zif/268 in the rat brain" @default.
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- W2023353731 doi "https://doi.org/10.1016/0304-3940(92)90023-z" @default.
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