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- W2023358315 abstract "Light and electron microscopic investigations were undertaken on adult rats in order to clarify the immediate effect of capsaicin on duodenal absorptive cells following intraduodenal and intragastric administration. Both natural and synthetic capsaicin administered by the same route for the same length of time produced identical morphologic alterations. Injury increased with duration of exposure, and within 2 min mitochondria were swollen with rarefied matrix and disorganized cristae. Increased numbers of free ribosomes and lysosomes and dilatation of endoplasmic reticulum and Golgi complexes were evident. Nuclei were shrunken and chromatin was clumped and marginated at the nuclear envelope. The consequences of these cellular alterations, as they relate to the function and physiology of the absorptive cell, are under investigation." @default.
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- W2023358315 date "1974-10-01" @default.
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- W2023358315 title "Duodenal mucosal response to the pungent principle of hot pepper (capsaicin) in the rat: Light and electron microscopic study" @default.
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- W2023358315 doi "https://doi.org/10.1016/0041-008x(74)90256-7" @default.
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