FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2023359807> ?p ?o ?g. }

• W2023359807 endingPage "717" @default.
• W2023359807 startingPage "710" @default.
• W2023359807 abstract "For thousands of years antlers have been used in Asian countries to promote rapid healing, treat weight loss, slow growth in children, strengthen weak bones, and alleviate cold hands and feet.The present study was performed to examine the effect of fermentation on the ability of antler to act as a stimulator of bone growth.This study used pre-osteoblast MC3T3-E1 cells to examine factors related to bone growth, such as cell proliferation, production of alkaline phosphatase (ALP), and deposition of extracellular matrix proteins (e.g., collagens, osteonectin, bone sialoprotein (BSP)), via the treatment of non-fermented and fermented antler.Antler fermentation using Cordyceps militaris was carried out at 25°C for seven days. The total content of sugar, sialic acid, and protein increased with fermentation time. Cell proliferation was greater in the fermented antler- (FA-) treated groups than in the NFA- (non-fermented antler-) treated groups, in which proliferation increased significantly up to 137% of the basal value. Significant increases in mRNA expression and ALP activity were found at FA concentrations of 50-100 μg/ml; at 100 μg/ml the activity had increased 119% compared to the control activity. For NFA and FA the expression levels of type I collagen mRNA significantly increased in a dose-dependent manner at all treatment doses. However, significant differences between the antler groups were not observed. Mineralization significantly increased by NFA and FA treatment to 183% and 241%, respectively, when compared to colostrum, as a positive control (165%).Antler treatment increased the proliferation of osteoblasts and bone matrix proteins, such as type I collagen and BSP. Antler fermented with Cordyceps militaris showed enhanced activity, and its stimulatory effects on cell proliferation and ALP production were greater than those of NFA. We surmise that these increases in activity were related to increased sialic acid content. Therefore, the results of this study suggest that the physiological effects of antler, including bone growth, may be increased through the fermentation process." @default.
• W2023359807 created "2016-06-24" @default.
• W2023359807 creator A5021530171 @default.
• W2023359807 creator A5030787538 @default.
• W2023359807 creator A5045922502 @default.
• W2023359807 creator A5047355512 @default.
• W2023359807 creator A5055100242 @default.
• W2023359807 creator A5062715114 @default.
• W2023359807 creator A5063515501 @default.
• W2023359807 creator A5070088029 @default.
• W2023359807 creator A5079848254 @default.
• W2023359807 date "2011-01-01" @default.
• W2023359807 modified "2023-09-26" @default.
• W2023359807 title "Stimulation of osteoblastic differentiation and mineralization in MC3T3-E1 cells by antler and fermented antler using Cordyceps militaris" @default.
• W2023359807 cites W1500005258 @default.
• W2023359807 cites W1580023435 @default.
• W2023359807 cites W1962695370 @default.
• W2023359807 cites W1968834637 @default.
• W2023359807 cites W1974242280 @default.
• W2023359807 cites W1978534816 @default.
• W2023359807 cites W1982043015 @default.
• W2023359807 cites W1983601471 @default.
• W2023359807 cites W1988447859 @default.
• W2023359807 cites W1988779088 @default.
• W2023359807 cites W1989308141 @default.
• W2023359807 cites W1992704723 @default.
• W2023359807 cites W2001758369 @default.
• W2023359807 cites W2021846846 @default.
• W2023359807 cites W2024941123 @default.
• W2023359807 cites W2037133888 @default.
• W2023359807 cites W2047616179 @default.
• W2023359807 cites W2051818188 @default.
• W2023359807 cites W2055872690 @default.
• W2023359807 cites W2057635936 @default.
• W2023359807 cites W2060229928 @default.
• W2023359807 cites W2069074659 @default.
• W2023359807 cites W2079265078 @default.
• W2023359807 cites W2086094439 @default.
• W2023359807 cites W2092625282 @default.
• W2023359807 cites W2100499337 @default.
• W2023359807 cites W2119274577 @default.
• W2023359807 cites W2128763439 @default.
• W2023359807 cites W2161278579 @default.
• W2023359807 cites W2162088346 @default.
• W2023359807 doi "https://doi.org/10.1016/j.jep.2010.10.047" @default.
• W2023359807 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/21040772" @default.
• W2023359807 hasPublicationYear "2011" @default.
• W2023359807 type Work @default.
• W2023359807 sameAs 2023359807 @default.
• W2023359807 citedByCount "31" @default.
• W2023359807 countsByYear W20233598072012 @default.
• W2023359807 countsByYear W20233598072013 @default.
• W2023359807 countsByYear W20233598072014 @default.
• W2023359807 countsByYear W20233598072015 @default.
• W2023359807 countsByYear W20233598072016 @default.
• W2023359807 countsByYear W20233598072017 @default.
• W2023359807 countsByYear W20233598072018 @default.
• W2023359807 countsByYear W20233598072019 @default.
• W2023359807 countsByYear W20233598072020 @default.
• W2023359807 countsByYear W20233598072021 @default.
• W2023359807 countsByYear W20233598072022 @default.
• W2023359807 crossrefType "journal-article" @default.
• W2023359807 hasAuthorship W2023359807A5021530171 @default.
• W2023359807 hasAuthorship W2023359807A5030787538 @default.
• W2023359807 hasAuthorship W2023359807A5045922502 @default.
• W2023359807 hasAuthorship W2023359807A5047355512 @default.
• W2023359807 hasAuthorship W2023359807A5055100242 @default.
• W2023359807 hasAuthorship W2023359807A5062715114 @default.
• W2023359807 hasAuthorship W2023359807A5063515501 @default.
• W2023359807 hasAuthorship W2023359807A5070088029 @default.
• W2023359807 hasAuthorship W2023359807A5079848254 @default.
• W2023359807 hasConcept C100544194 @default.
• W2023359807 hasConcept C126322002 @default.
• W2023359807 hasConcept C131075544 @default.
• W2023359807 hasConcept C134018914 @default.
• W2023359807 hasConcept C160160445 @default.
• W2023359807 hasConcept C181199279 @default.
• W2023359807 hasConcept C185592680 @default.
• W2023359807 hasConcept C18903297 @default.
• W2023359807 hasConcept C202751555 @default.
• W2023359807 hasConcept C2776432469 @default.
• W2023359807 hasConcept C2777361732 @default.
• W2023359807 hasConcept C2778260815 @default.
• W2023359807 hasConcept C55493867 @default.
• W2023359807 hasConcept C62112901 @default.
• W2023359807 hasConcept C71924100 @default.
• W2023359807 hasConcept C86803240 @default.
• W2023359807 hasConceptScore W2023359807C100544194 @default.
• W2023359807 hasConceptScore W2023359807C126322002 @default.
• W2023359807 hasConceptScore W2023359807C131075544 @default.
• W2023359807 hasConceptScore W2023359807C134018914 @default.
• W2023359807 hasConceptScore W2023359807C160160445 @default.
• W2023359807 hasConceptScore W2023359807C181199279 @default.
• W2023359807 hasConceptScore W2023359807C185592680 @default.
• W2023359807 hasConceptScore W2023359807C18903297 @default.
• W2023359807 hasConceptScore W2023359807C202751555 @default.
• W2023359807 hasConceptScore W2023359807C2776432469 @default.
• W2023359807 hasConceptScore W2023359807C2777361732 @default.

• next