FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2023361587> ?p ?o ?g. }

• W2023361587 endingPage "1104" @default.
• W2023361587 startingPage "1098" @default.
• W2023361587 abstract "The objective of this study was to explore the relationship between serum levels of β2-microglobulin (β2MG), which some studies suggest reflect disease activity in systemic lupus erythematosus (SLE), and various clinical and immunological markers of disease activity in SLE. Twenty-six SLE patients and 10 healthy controls were included. Disease activity was assessed by: SLEDAI, 24 hr-proteinuria, circulating levels of complement C3, anti-double-stranded DNA (anti-dsDNA), β2MG and various pro-inflammatory and anti-inflammatory cytokines (IL-6, IL-8, IL-10, IL-18) measured with a multiplex assay, IFN-α assessed with a reporter gene assay, and a combined expression score of 12 IFN-α inducible genes in peripheral blood mononuclear cells. Median serum levels of β2MG were significantly higher in SLE patients vs controls (2.8 mg/L, range: 1.1–21.6 and 1.2 mg/L, range: 0.9–1.7, respectively, p < 0.001). β2MG was correlated with SLEDAI score ( R = 0.68, p < 0.001), 24 hr-proteinuria ( R = 0.64, p < 0.001), and complement C3 ( R = −0.52, p = 0.007). The cytokines were significantly correlated with β2MG: IL-6 ( R = 0.45, p = 0.02), IL-8 ( R = 0.75, p < 0.001), IL-10 ( R = 0.67, p < 0.001) and IL-18 ( R = 0.71, p < 0.001) as were serum IFN-α ( R = 0.45, p = 0.02) and the IFN-α inducible gene-score ( R = 0.51, p = 0.01). The results support that β2MG may serve as a marker of disease activity in SLE. The correlations with the measured cytokines indicate that increased β2MG in SLE reflects immunological activity." @default.
• W2023361587 created "2016-06-24" @default.
• W2023361587 creator A5006360414 @default.
• W2023361587 creator A5008837949 @default.
• W2023361587 creator A5010450706 @default.
• W2023361587 creator A5046869985 @default.
• W2023361587 creator A5056255933 @default.
• W2023361587 creator A5065383342 @default.
• W2023361587 creator A5066700328 @default.
• W2023361587 creator A5071217796 @default.
• W2023361587 creator A5086180632 @default.
• W2023361587 date "2012-05-10" @default.
• W2023361587 modified "2023-10-14" @default.
• W2023361587 title "Increased serum β2-microglobulin is associated with clinical and immunological markers of disease activity in systemic lupus erythematosus patients" @default.
• W2023361587 cites W1515615230 @default.
• W2023361587 cites W1900281246 @default.
• W2023361587 cites W1963552316 @default.
• W2023361587 cites W1966335538 @default.
• W2023361587 cites W1976316527 @default.
• W2023361587 cites W1994094364 @default.
• W2023361587 cites W1996505345 @default.
• W2023361587 cites W2016561383 @default.
• W2023361587 cites W2020410667 @default.
• W2023361587 cites W2027632198 @default.
• W2023361587 cites W2030520505 @default.
• W2023361587 cites W2036072927 @default.
• W2023361587 cites W2042323600 @default.
• W2023361587 cites W2056727695 @default.
• W2023361587 cites W2064999867 @default.
• W2023361587 cites W2072465606 @default.
• W2023361587 cites W2079320171 @default.
• W2023361587 cites W2080457429 @default.
• W2023361587 cites W2084988989 @default.
• W2023361587 cites W2097556922 @default.
• W2023361587 cites W2098412155 @default.
• W2023361587 cites W2104731054 @default.
• W2023361587 cites W2106273198 @default.
• W2023361587 cites W2122586308 @default.
• W2023361587 cites W2132022654 @default.
• W2023361587 cites W2139905928 @default.
• W2023361587 cites W2146203649 @default.
• W2023361587 cites W2160100702 @default.
• W2023361587 cites W2168331207 @default.
• W2023361587 cites W2168888135 @default.
• W2023361587 cites W4313309916 @default.
• W2023361587 doi "https://doi.org/10.1177/0961203312447668" @default.
• W2023361587 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/22577117" @default.
• W2023361587 hasPublicationYear "2012" @default.
• W2023361587 type Work @default.
• W2023361587 sameAs 2023361587 @default.
• W2023361587 citedByCount "33" @default.
• W2023361587 countsByYear W20233615872012 @default.
• W2023361587 countsByYear W20233615872013 @default.
• W2023361587 countsByYear W20233615872014 @default.
• W2023361587 countsByYear W20233615872015 @default.
• W2023361587 countsByYear W20233615872017 @default.
• W2023361587 countsByYear W20233615872018 @default.
• W2023361587 countsByYear W20233615872019 @default.
• W2023361587 countsByYear W20233615872020 @default.
• W2023361587 countsByYear W20233615872021 @default.
• W2023361587 countsByYear W20233615872022 @default.
• W2023361587 countsByYear W20233615872023 @default.
• W2023361587 crossrefType "journal-article" @default.
• W2023361587 hasAuthorship W2023361587A5006360414 @default.
• W2023361587 hasAuthorship W2023361587A5008837949 @default.
• W2023361587 hasAuthorship W2023361587A5010450706 @default.
• W2023361587 hasAuthorship W2023361587A5046869985 @default.
• W2023361587 hasAuthorship W2023361587A5056255933 @default.
• W2023361587 hasAuthorship W2023361587A5065383342 @default.
• W2023361587 hasAuthorship W2023361587A5066700328 @default.
• W2023361587 hasAuthorship W2023361587A5071217796 @default.
• W2023361587 hasAuthorship W2023361587A5086180632 @default.
• W2023361587 hasConcept C126322002 @default.
• W2023361587 hasConcept C137061746 @default.
• W2023361587 hasConcept C159654299 @default.
• W2023361587 hasConcept C202751555 @default.
• W2023361587 hasConcept C203014093 @default.
• W2023361587 hasConcept C21957315 @default.
• W2023361587 hasConcept C2775915377 @default.
• W2023361587 hasConcept C2776912625 @default.
• W2023361587 hasConcept C2779134260 @default.
• W2023361587 hasConcept C2779561371 @default.
• W2023361587 hasConcept C2779912601 @default.
• W2023361587 hasConcept C2780091579 @default.
• W2023361587 hasConcept C2780380361 @default.
• W2023361587 hasConcept C55493867 @default.
• W2023361587 hasConcept C71924100 @default.
• W2023361587 hasConcept C86803240 @default.
• W2023361587 hasConceptScore W2023361587C126322002 @default.
• W2023361587 hasConceptScore W2023361587C137061746 @default.
• W2023361587 hasConceptScore W2023361587C159654299 @default.
• W2023361587 hasConceptScore W2023361587C202751555 @default.
• W2023361587 hasConceptScore W2023361587C203014093 @default.
• W2023361587 hasConceptScore W2023361587C21957315 @default.
• W2023361587 hasConceptScore W2023361587C2775915377 @default.
• W2023361587 hasConceptScore W2023361587C2776912625 @default.
• W2023361587 hasConceptScore W2023361587C2779134260 @default.
• W2023361587 hasConceptScore W2023361587C2779561371 @default.

• next