Matches in SemOpenAlex for { <https://semopenalex.org/work/W2023361688> ?p ?o ?g. }
- W2023361688 endingPage "295" @default.
- W2023361688 startingPage "287" @default.
- W2023361688 abstract "The population of Erechim, Southern Brazil, is characterized by a high incidence of ocular toxoplasmosis, which is presumed to be of acquired origin. We wished to compare the local specific humoral immune response of individuals from this region with that of Swiss patients suffering from the same disease. Paired samples of aqueous humor and serum were withdrawn from 27 Brazilian and 50 Swiss patients presenting consecutively with active ocular toxoplasmosis. The total and specific levels of IgG in each of these were determined. The populations did not differ with respect either to age or sex. The serum levels of total IgG in Brazilian (10.8 g/l) and Swiss patients (11.1 g/l) were similar (p = 0.499), but the aqueous humor ones were higher in the former group (95 vs. 20 mg/l; p = 0.0001). The systemic and local levels of specific IgG were likewise higher in Brazilian patients [206 i.u. vs. 72 i.u. (p = 0.001) and 14 i.u. vs. 4 i.u. (p = 0.005), respectively] and the number of individuals without detectable levels of local specific IgG was correspondingly lower (11% vs. 54%; p = 0.0005). The Goldmann-Witmer coefficient (an index of local specific antibody production) did not differ between Brazilian and Swiss patients (2.1 vs. 0.08, respectively; p = 0.107). Our findings are indicative of a more pronounced uveovascular barrier breakdown in Brazilians than in Swiss patients with active ocular toxoplasmosis. That the systemic and local specific immune response is weaker in Swiss than in Brazilian patients has not been hitherto documented. This finding may reflect differences in the immunological handling of the infection." @default.
- W2023361688 created "2016-06-24" @default.
- W2023361688 creator A5003673246 @default.
- W2023361688 creator A5014806709 @default.
- W2023361688 creator A5023989060 @default.
- W2023361688 creator A5075913766 @default.
- W2023361688 creator A5075928522 @default.
- W2023361688 creator A5076181472 @default.
- W2023361688 creator A5078017131 @default.
- W2023361688 date "2005-08-22" @default.
- W2023361688 modified "2023-10-02" @default.
- W2023361688 title "Specific antibody levels in the aqueous humor and serum of two distinct populations of patients with ocular toxoplasmosis" @default.
- W2023361688 cites W1482306167 @default.
- W2023361688 cites W1482748249 @default.
- W2023361688 cites W1486065202 @default.
- W2023361688 cites W1519585659 @default.
- W2023361688 cites W1532203948 @default.
- W2023361688 cites W154847612 @default.
- W2023361688 cites W1572515873 @default.
- W2023361688 cites W190025028 @default.
- W2023361688 cites W1951511903 @default.
- W2023361688 cites W1961636599 @default.
- W2023361688 cites W1967277300 @default.
- W2023361688 cites W1968620704 @default.
- W2023361688 cites W1971561091 @default.
- W2023361688 cites W1972508040 @default.
- W2023361688 cites W1994712912 @default.
- W2023361688 cites W1995703283 @default.
- W2023361688 cites W1999539811 @default.
- W2023361688 cites W2005530804 @default.
- W2023361688 cites W2006803324 @default.
- W2023361688 cites W2012159847 @default.
- W2023361688 cites W2012695904 @default.
- W2023361688 cites W2016341989 @default.
- W2023361688 cites W2033202315 @default.
- W2023361688 cites W2035319065 @default.
- W2023361688 cites W2035378842 @default.
- W2023361688 cites W2038741415 @default.
- W2023361688 cites W2048098533 @default.
- W2023361688 cites W2051738762 @default.
- W2023361688 cites W2063944657 @default.
- W2023361688 cites W2067157751 @default.
- W2023361688 cites W2067589649 @default.
- W2023361688 cites W2073897003 @default.
- W2023361688 cites W2074298719 @default.
- W2023361688 cites W2080930963 @default.
- W2023361688 cites W2091043696 @default.
- W2023361688 cites W2092054292 @default.
- W2023361688 cites W2095674426 @default.
- W2023361688 cites W2096086575 @default.
- W2023361688 cites W2108632762 @default.
- W2023361688 cites W2111180084 @default.
- W2023361688 cites W2121461139 @default.
- W2023361688 cites W2123391954 @default.
- W2023361688 cites W2127129138 @default.
- W2023361688 cites W2130747475 @default.
- W2023361688 cites W2141449986 @default.
- W2023361688 cites W2141763791 @default.
- W2023361688 cites W2142283065 @default.
- W2023361688 cites W2144049958 @default.
- W2023361688 cites W2149914768 @default.
- W2023361688 cites W2150818634 @default.
- W2023361688 cites W2159252441 @default.
- W2023361688 cites W2168752297 @default.
- W2023361688 cites W224319976 @default.
- W2023361688 cites W232202339 @default.
- W2023361688 cites W2396802694 @default.
- W2023361688 cites W2410796272 @default.
- W2023361688 cites W2597875165 @default.
- W2023361688 cites W33927298 @default.
- W2023361688 doi "https://doi.org/10.1016/j.ijmm.2005.03.005" @default.
- W2023361688 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/16128403" @default.
- W2023361688 hasPublicationYear "2005" @default.
- W2023361688 type Work @default.
- W2023361688 sameAs 2023361688 @default.
- W2023361688 citedByCount "16" @default.
- W2023361688 countsByYear W20233616882012 @default.
- W2023361688 countsByYear W20233616882013 @default.
- W2023361688 countsByYear W20233616882014 @default.
- W2023361688 countsByYear W20233616882016 @default.
- W2023361688 countsByYear W20233616882018 @default.
- W2023361688 countsByYear W20233616882019 @default.
- W2023361688 countsByYear W20233616882020 @default.
- W2023361688 crossrefType "journal-article" @default.
- W2023361688 hasAuthorship W2023361688A5003673246 @default.
- W2023361688 hasAuthorship W2023361688A5014806709 @default.
- W2023361688 hasAuthorship W2023361688A5023989060 @default.
- W2023361688 hasAuthorship W2023361688A5075913766 @default.
- W2023361688 hasAuthorship W2023361688A5075928522 @default.
- W2023361688 hasAuthorship W2023361688A5076181472 @default.
- W2023361688 hasAuthorship W2023361688A5078017131 @default.
- W2023361688 hasConcept C120665830 @default.
- W2023361688 hasConcept C121332964 @default.
- W2023361688 hasConcept C126322002 @default.
- W2023361688 hasConcept C159654299 @default.
- W2023361688 hasConcept C203014093 @default.
- W2023361688 hasConcept C2778062946 @default.
- W2023361688 hasConcept C2908647359 @default.