Matches in SemOpenAlex for { <https://semopenalex.org/work/W2023361859> ?p ?o ?g. }
Showing items 1 to 88 of
88
with 100 items per page.
- W2023361859 endingPage "674" @default.
- W2023361859 startingPage "669" @default.
- W2023361859 abstract "A new high-performance liquid chromatographic/electrospray ionization tandem mass spectrometric (HPLC/ESI-MS/MS) method was developed for the simultaneous quantification of 5-fluorouracil (5FU), methotrexate (MTX) and cyclophosphamide (CP) in environmental samples. These compounds, commonly used in the treatment of cancer, are recognized as genotoxic. In order to estimate the occupational exposure of hospital personnel handling these drugs, wipe samples were taken from the working surfaces and directly analyzed (with trophosphamide as internal standard) using a reversed-phase capillary column and MS/MS detection. This is the first HPLC/MS/MS method for the simultaneous determination of 5FU, MTX and CP. The present method offers high sensitivity, with detection limits of 1.1 µg l−1 for MTX and CP and 33.3 µg l−1 for 5FU, avoiding any sample preconcentration procedure. Rapidity, specificity, high accuracy (mean values between 92.4 and 99.9%) and precision (mean RSD values between 3.4 and 12.1%) make the method suitable for the routine determination of these three antineoplastic drugs. Copyright © 2005 John Wiley & Sons, Ltd." @default.
- W2023361859 created "2016-06-24" @default.
- W2023361859 creator A5017927535 @default.
- W2023361859 creator A5028533131 @default.
- W2023361859 creator A5028790323 @default.
- W2023361859 creator A5078547578 @default.
- W2023361859 date "2005-01-01" @default.
- W2023361859 modified "2023-10-16" @default.
- W2023361859 title "A new high-performance liquid chromatographic/electrospray ionization tandem mass spectrometric method for the simultaneous determination of cyclophosphamide, methotrexate and 5-fluorouracil as markers of surface contamination for occupational exposure monitoring" @default.
- W2023361859 cites W1988865052 @default.
- W2023361859 cites W1993384130 @default.
- W2023361859 cites W2000542203 @default.
- W2023361859 cites W2008401150 @default.
- W2023361859 cites W2012261641 @default.
- W2023361859 cites W2027200280 @default.
- W2023361859 cites W2030452904 @default.
- W2023361859 cites W2035684949 @default.
- W2023361859 cites W2042619082 @default.
- W2023361859 cites W2050678041 @default.
- W2023361859 cites W2085433011 @default.
- W2023361859 cites W2091655114 @default.
- W2023361859 cites W2096274271 @default.
- W2023361859 cites W2153596481 @default.
- W2023361859 cites W2336552889 @default.
- W2023361859 doi "https://doi.org/10.1002/jms.840" @default.
- W2023361859 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/15739158" @default.
- W2023361859 hasPublicationYear "2005" @default.
- W2023361859 type Work @default.
- W2023361859 sameAs 2023361859 @default.
- W2023361859 citedByCount "49" @default.
- W2023361859 countsByYear W20233618592012 @default.
- W2023361859 countsByYear W20233618592013 @default.
- W2023361859 countsByYear W20233618592014 @default.
- W2023361859 countsByYear W20233618592015 @default.
- W2023361859 countsByYear W20233618592016 @default.
- W2023361859 countsByYear W20233618592017 @default.
- W2023361859 countsByYear W20233618592018 @default.
- W2023361859 countsByYear W20233618592022 @default.
- W2023361859 countsByYear W20233618592023 @default.
- W2023361859 crossrefType "journal-article" @default.
- W2023361859 hasAuthorship W2023361859A5017927535 @default.
- W2023361859 hasAuthorship W2023361859A5028533131 @default.
- W2023361859 hasAuthorship W2023361859A5028790323 @default.
- W2023361859 hasAuthorship W2023361859A5078547578 @default.
- W2023361859 hasConcept C119128265 @default.
- W2023361859 hasConcept C162356407 @default.
- W2023361859 hasConcept C179998833 @default.
- W2023361859 hasConcept C185592680 @default.
- W2023361859 hasConcept C194451485 @default.
- W2023361859 hasConcept C203014093 @default.
- W2023361859 hasConcept C2781059491 @default.
- W2023361859 hasConcept C31827203 @default.
- W2023361859 hasConcept C40684141 @default.
- W2023361859 hasConcept C43617362 @default.
- W2023361859 hasConcept C86803240 @default.
- W2023361859 hasConceptScore W2023361859C119128265 @default.
- W2023361859 hasConceptScore W2023361859C162356407 @default.
- W2023361859 hasConceptScore W2023361859C179998833 @default.
- W2023361859 hasConceptScore W2023361859C185592680 @default.
- W2023361859 hasConceptScore W2023361859C194451485 @default.
- W2023361859 hasConceptScore W2023361859C203014093 @default.
- W2023361859 hasConceptScore W2023361859C2781059491 @default.
- W2023361859 hasConceptScore W2023361859C31827203 @default.
- W2023361859 hasConceptScore W2023361859C40684141 @default.
- W2023361859 hasConceptScore W2023361859C43617362 @default.
- W2023361859 hasConceptScore W2023361859C86803240 @default.
- W2023361859 hasIssue "5" @default.
- W2023361859 hasLocation W20233618591 @default.
- W2023361859 hasLocation W20233618592 @default.
- W2023361859 hasOpenAccess W2023361859 @default.
- W2023361859 hasPrimaryLocation W20233618591 @default.
- W2023361859 hasRelatedWork W1974167529 @default.
- W2023361859 hasRelatedWork W1992846081 @default.
- W2023361859 hasRelatedWork W2014605936 @default.
- W2023361859 hasRelatedWork W2023232374 @default.
- W2023361859 hasRelatedWork W2027593566 @default.
- W2023361859 hasRelatedWork W2057490141 @default.
- W2023361859 hasRelatedWork W2069623463 @default.
- W2023361859 hasRelatedWork W2346859668 @default.
- W2023361859 hasRelatedWork W2772966011 @default.
- W2023361859 hasRelatedWork W3143827393 @default.
- W2023361859 hasVolume "40" @default.
- W2023361859 isParatext "false" @default.
- W2023361859 isRetracted "false" @default.
- W2023361859 magId "2023361859" @default.
- W2023361859 workType "article" @default.