Matches in SemOpenAlex for { <https://semopenalex.org/work/W2023365921> ?p ?o ?g. }
- W2023365921 endingPage "520" @default.
- W2023365921 startingPage "505" @default.
- W2023365921 abstract "We present a method to label and trace the lineage of multiple neural progenitors simultaneously in vertebrate animals via multiaddressable genome-integrative color (MAGIC) markers. We achieve permanent expression of combinatorial labels from new Brainbow transgenes introduced in embryonic neural progenitors with electroporation of transposon vectors. In the mouse forebrain and chicken spinal cord, this approach allows us to track neural progenitor's descent during pre- and postnatal neurogenesis or perinatal gliogenesis in long-term experiments. Color labels delineate cytoarchitecture, resolve spatially intermixed clones, and specify the lineage of astroglial subtypes and adult neural stem cells. Combining colors and subcellular locations provides an expanded marker palette to individualize clones. We show that this approach is also applicable to modulate specific signaling pathways in a mosaic manner while color-coding the status of individual cells regarding induced molecular perturbations. This method opens new avenues for clonal and functional analysis in varied experimental models and contexts." @default.
- W2023365921 created "2016-06-24" @default.
- W2023365921 creator A5004938919 @default.
- W2023365921 creator A5014215458 @default.
- W2023365921 creator A5018639480 @default.
- W2023365921 creator A5025789427 @default.
- W2023365921 creator A5029886936 @default.
- W2023365921 creator A5041125620 @default.
- W2023365921 creator A5042087592 @default.
- W2023365921 creator A5052755538 @default.
- W2023365921 creator A5053496442 @default.
- W2023365921 creator A5062676612 @default.
- W2023365921 creator A5067921141 @default.
- W2023365921 creator A5073469688 @default.
- W2023365921 creator A5086798625 @default.
- W2023365921 creator A5087561865 @default.
- W2023365921 date "2014-02-01" @default.
- W2023365921 modified "2023-10-13" @default.
- W2023365921 title "Multiplex Cell and Lineage Tracking with Combinatorial Labels" @default.
- W2023365921 cites W1503727145 @default.
- W2023365921 cites W1504807885 @default.
- W2023365921 cites W1538926863 @default.
- W2023365921 cites W1747944491 @default.
- W2023365921 cites W1916653587 @default.
- W2023365921 cites W1976217132 @default.
- W2023365921 cites W1985395763 @default.
- W2023365921 cites W1986281313 @default.
- W2023365921 cites W1987126633 @default.
- W2023365921 cites W1989244157 @default.
- W2023365921 cites W1989744780 @default.
- W2023365921 cites W1994323133 @default.
- W2023365921 cites W1996532711 @default.
- W2023365921 cites W1999543570 @default.
- W2023365921 cites W2001453133 @default.
- W2023365921 cites W2002687566 @default.
- W2023365921 cites W2003067279 @default.
- W2023365921 cites W2007079049 @default.
- W2023365921 cites W2007981920 @default.
- W2023365921 cites W2012049188 @default.
- W2023365921 cites W2017714955 @default.
- W2023365921 cites W2021593652 @default.
- W2023365921 cites W2025706827 @default.
- W2023365921 cites W2029782611 @default.
- W2023365921 cites W2032850366 @default.
- W2023365921 cites W2033319920 @default.
- W2023365921 cites W2035726898 @default.
- W2023365921 cites W2036442380 @default.
- W2023365921 cites W2038600043 @default.
- W2023365921 cites W2043272632 @default.
- W2023365921 cites W2045233939 @default.
- W2023365921 cites W2046560352 @default.
- W2023365921 cites W2048162805 @default.
- W2023365921 cites W2050797160 @default.
- W2023365921 cites W2052790148 @default.
- W2023365921 cites W2054870083 @default.
- W2023365921 cites W2055864348 @default.
- W2023365921 cites W2062860446 @default.
- W2023365921 cites W2062901218 @default.
- W2023365921 cites W2065045053 @default.
- W2023365921 cites W2066362124 @default.
- W2023365921 cites W2070255306 @default.
- W2023365921 cites W2076507262 @default.
- W2023365921 cites W2078238075 @default.
- W2023365921 cites W2080322528 @default.
- W2023365921 cites W2081028995 @default.
- W2023365921 cites W2089518215 @default.
- W2023365921 cites W2091404816 @default.
- W2023365921 cites W2104010513 @default.
- W2023365921 cites W2110232607 @default.
- W2023365921 cites W2115734610 @default.
- W2023365921 cites W2126343030 @default.
- W2023365921 cites W2136086257 @default.
- W2023365921 cites W2138800935 @default.
- W2023365921 cites W2147987903 @default.
- W2023365921 cites W2155205967 @default.
- W2023365921 cites W2162338413 @default.
- W2023365921 cites W2163024465 @default.
- W2023365921 cites W2163958669 @default.
- W2023365921 cites W2166700927 @default.
- W2023365921 cites W2166791153 @default.
- W2023365921 cites W2167279371 @default.
- W2023365921 cites W2168080864 @default.
- W2023365921 cites W2168901267 @default.
- W2023365921 cites W4232322096 @default.
- W2023365921 doi "https://doi.org/10.1016/j.neuron.2013.12.016" @default.
- W2023365921 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/24507188" @default.
- W2023365921 hasPublicationYear "2014" @default.
- W2023365921 type Work @default.
- W2023365921 sameAs 2023365921 @default.
- W2023365921 citedByCount "137" @default.
- W2023365921 countsByYear W20233659212014 @default.
- W2023365921 countsByYear W20233659212015 @default.
- W2023365921 countsByYear W20233659212016 @default.
- W2023365921 countsByYear W20233659212017 @default.
- W2023365921 countsByYear W20233659212018 @default.
- W2023365921 countsByYear W20233659212019 @default.
- W2023365921 countsByYear W20233659212020 @default.
- W2023365921 countsByYear W20233659212021 @default.