FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2023366190> ?p ?o ?g. }

• W2023366190 endingPage "50" @default.
• W2023366190 startingPage "45" @default.
• W2023366190 abstract "The reperfusion of ischemic tissue often delays its physiological and functional recovery; this paradoxical effect is ascribed to increased release of free radicals including O(2)(-) and NO. For these reasons, scavenging reactive oxygen species or inhibition the NO synthesis has been shown to result in an enhanced neuronal survival after cerebral ischemia. Many authors believe that therapy for stroke patients would be a cocktail of drugs with various mechanisms of action. Combination therapy is a difficult and complicated avenue for drug development because of the possibility of drug-drug interactions. An alternative approach would be to combine multiple activities within the same compound. In consideration of the free-radical scavenging and inhibitory effect on NOS of various natural and synthetic compounds, the aim of this study was to analyze the antioxidant properties of some imidazole derivatives previously synthesized in our laboratory. Results obtained in the present study provide evidence that tested compounds exhibit interesting antioxidant properties, expressed either by their capacity to scavenge free radicals or their ability to reduce lipid peroxidation. In particular, compounds A and B represent chemical structures which can be easily modified to improve the observed antioxidant properties and to provide new therapeutic strategies focused on multiple downstream events." @default.
• W2023366190 created "2016-06-24" @default.
• W2023366190 creator A5018322905 @default.
• W2023366190 creator A5040847244 @default.
• W2023366190 creator A5049203178 @default.
• W2023366190 creator A5079108745 @default.
• W2023366190 creator A5084855762 @default.
• W2023366190 creator A5086602723 @default.
• W2023366190 date "2006-02-01" @default.
• W2023366190 modified "2023-10-01" @default.
• W2023366190 title "Imidazole derivatives as antioxidants and selective inhibitors of nNOS" @default.
• W2023366190 cites W1853037896 @default.
• W2023366190 cites W1918909434 @default.
• W2023366190 cites W1978020415 @default.
• W2023366190 cites W1985481345 @default.
• W2023366190 cites W1996898259 @default.
• W2023366190 cites W1997351400 @default.
• W2023366190 cites W2007250122 @default.
• W2023366190 cites W2016597337 @default.
• W2023366190 cites W2024862570 @default.
• W2023366190 cites W2027280736 @default.
• W2023366190 cites W2028676745 @default.
• W2023366190 cites W2034226621 @default.
• W2023366190 cites W2041042567 @default.
• W2023366190 cites W2045339715 @default.
• W2023366190 cites W2047843548 @default.
• W2023366190 cites W2053209378 @default.
• W2023366190 cites W2058137293 @default.
• W2023366190 cites W2058577077 @default.
• W2023366190 cites W2059245012 @default.
• W2023366190 cites W2059640915 @default.
• W2023366190 cites W2067007843 @default.
• W2023366190 cites W2081571747 @default.
• W2023366190 cites W2084494271 @default.
• W2023366190 cites W2088195616 @default.
• W2023366190 cites W2119408590 @default.
• W2023366190 cites W2134404886 @default.
• W2023366190 cites W2140936548 @default.
• W2023366190 cites W2152384354 @default.
• W2023366190 cites W2169079203 @default.
• W2023366190 cites W2178173120 @default.
• W2023366190 cites W2316145923 @default.
• W2023366190 cites W287575487 @default.
• W2023366190 doi "https://doi.org/10.1016/j.niox.2005.09.005" @default.
• W2023366190 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/16275025" @default.
• W2023366190 hasPublicationYear "2006" @default.
• W2023366190 type Work @default.
• W2023366190 sameAs 2023366190 @default.
• W2023366190 citedByCount "36" @default.
• W2023366190 countsByYear W20233661902012 @default.
• W2023366190 countsByYear W20233661902013 @default.
• W2023366190 countsByYear W20233661902014 @default.
• W2023366190 countsByYear W20233661902015 @default.
• W2023366190 countsByYear W20233661902016 @default.
• W2023366190 countsByYear W20233661902017 @default.
• W2023366190 countsByYear W20233661902018 @default.
• W2023366190 countsByYear W20233661902019 @default.
• W2023366190 countsByYear W20233661902020 @default.
• W2023366190 countsByYear W20233661902021 @default.
• W2023366190 countsByYear W20233661902022 @default.
• W2023366190 countsByYear W20233661902023 @default.
• W2023366190 crossrefType "journal-article" @default.
• W2023366190 hasAuthorship W2023366190A5018322905 @default.
• W2023366190 hasAuthorship W2023366190A5040847244 @default.
• W2023366190 hasAuthorship W2023366190A5049203178 @default.
• W2023366190 hasAuthorship W2023366190A5079108745 @default.
• W2023366190 hasAuthorship W2023366190A5084855762 @default.
• W2023366190 hasAuthorship W2023366190A5086602723 @default.
• W2023366190 hasConcept C139066938 @default.
• W2023366190 hasConcept C185592680 @default.
• W2023366190 hasConcept C21951064 @default.
• W2023366190 hasConcept C2778004101 @default.
• W2023366190 hasConcept C2780035454 @default.
• W2023366190 hasConcept C2780829032 @default.
• W2023366190 hasConcept C2780874372 @default.
• W2023366190 hasConcept C48349386 @default.
• W2023366190 hasConcept C55493867 @default.
• W2023366190 hasConcept C71924100 @default.
• W2023366190 hasConcept C98274493 @default.
• W2023366190 hasConceptScore W2023366190C139066938 @default.
• W2023366190 hasConceptScore W2023366190C185592680 @default.
• W2023366190 hasConceptScore W2023366190C21951064 @default.
• W2023366190 hasConceptScore W2023366190C2778004101 @default.
• W2023366190 hasConceptScore W2023366190C2780035454 @default.
• W2023366190 hasConceptScore W2023366190C2780829032 @default.
• W2023366190 hasConceptScore W2023366190C2780874372 @default.
• W2023366190 hasConceptScore W2023366190C48349386 @default.
• W2023366190 hasConceptScore W2023366190C55493867 @default.
• W2023366190 hasConceptScore W2023366190C71924100 @default.
• W2023366190 hasConceptScore W2023366190C98274493 @default.
• W2023366190 hasIssue "1" @default.
• W2023366190 hasLocation W20233661901 @default.
• W2023366190 hasLocation W20233661902 @default.
• W2023366190 hasOpenAccess W2023366190 @default.
• W2023366190 hasPrimaryLocation W20233661901 @default.
• W2023366190 hasRelatedWork W1470000624 @default.
• W2023366190 hasRelatedWork W1969404129 @default.
• W2023366190 hasRelatedWork W2084186860 @default.

• next