Matches in SemOpenAlex for { <https://semopenalex.org/work/W2023374767> ?p ?o ?g. }
- W2023374767 endingPage "1783" @default.
- W2023374767 startingPage "1769" @default.
- W2023374767 abstract "Neural stem (NS) cells are a self-renewing population of symmetrically dividing multipotent radial glia-like stem cells, characterized by homogeneous expansion in monolayer. Here we report that fetal NS cells isolated from different regions of the developing mouse nervous system behave in a similar manner with respect to self-renewal and neuropotency, but exhibit distinct positional identities. For example, NS cells from the neocortex maintain the expression of anterior transcription factors, including Otx2 and Foxg1, while Hoxb4 and Hoxb9 are uniquely found in spinal cord-derived NS cells. This molecular signature was stable for over 20 passages and was strictly linked to the developmental stage of the donor, because only NS cells derived from E14.5 cortex, and not those derived from E12.5 cortex, carried a consistent transcription factor profile. We also showed that traits of this positional code are maintained during neuronal differentiation, leading to the generation of electrophysiologically active neurons, even if they do not acquire a complete neurochemical identity." @default.
- W2023374767 created "2016-06-24" @default.
- W2023374767 creator A5011206616 @default.
- W2023374767 creator A5025250272 @default.
- W2023374767 creator A5041987246 @default.
- W2023374767 creator A5042005526 @default.
- W2023374767 creator A5043713924 @default.
- W2023374767 creator A5043985250 @default.
- W2023374767 creator A5047378476 @default.
- W2023374767 creator A5047383675 @default.
- W2023374767 creator A5051102321 @default.
- W2023374767 creator A5077061516 @default.
- W2023374767 creator A5077975999 @default.
- W2023374767 creator A5085954195 @default.
- W2023374767 creator A5089345009 @default.
- W2023374767 date "2010-10-28" @default.
- W2023374767 modified "2023-10-18" @default.
- W2023374767 title "Preservation of positional identity in fetus-derived neural stem (NS) cells from different mouse central nervous system compartments" @default.
- W2023374767 cites W1507310985 @default.
- W2023374767 cites W1825846406 @default.
- W2023374767 cites W1859730138 @default.
- W2023374767 cites W1875709550 @default.
- W2023374767 cites W1965350971 @default.
- W2023374767 cites W1977811875 @default.
- W2023374767 cites W1979762984 @default.
- W2023374767 cites W1980217666 @default.
- W2023374767 cites W1994203685 @default.
- W2023374767 cites W1994514343 @default.
- W2023374767 cites W2000156766 @default.
- W2023374767 cites W2013596279 @default.
- W2023374767 cites W2014956953 @default.
- W2023374767 cites W2016350172 @default.
- W2023374767 cites W2018235103 @default.
- W2023374767 cites W2021692265 @default.
- W2023374767 cites W2023930954 @default.
- W2023374767 cites W2025618811 @default.
- W2023374767 cites W2040118612 @default.
- W2023374767 cites W2040682085 @default.
- W2023374767 cites W2043655216 @default.
- W2023374767 cites W2044756233 @default.
- W2023374767 cites W2052624565 @default.
- W2023374767 cites W2069815915 @default.
- W2023374767 cites W2085006580 @default.
- W2023374767 cites W2085870515 @default.
- W2023374767 cites W2091628112 @default.
- W2023374767 cites W2095389581 @default.
- W2023374767 cites W2100100832 @default.
- W2023374767 cites W2103635980 @default.
- W2023374767 cites W2103903979 @default.
- W2023374767 cites W2125908939 @default.
- W2023374767 cites W2135107819 @default.
- W2023374767 cites W2136930579 @default.
- W2023374767 cites W2150014868 @default.
- W2023374767 cites W2155228504 @default.
- W2023374767 cites W2165682071 @default.
- W2023374767 cites W2165981171 @default.
- W2023374767 cites W2172291646 @default.
- W2023374767 cites W2223979714 @default.
- W2023374767 cites W2234814159 @default.
- W2023374767 cites W2794178849 @default.
- W2023374767 doi "https://doi.org/10.1007/s00018-010-0548-7" @default.
- W2023374767 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/27405607" @default.
- W2023374767 hasPublicationYear "2010" @default.
- W2023374767 type Work @default.
- W2023374767 sameAs 2023374767 @default.
- W2023374767 citedByCount "26" @default.
- W2023374767 countsByYear W20233747672012 @default.
- W2023374767 countsByYear W20233747672013 @default.
- W2023374767 countsByYear W20233747672014 @default.
- W2023374767 countsByYear W20233747672015 @default.
- W2023374767 countsByYear W20233747672016 @default.
- W2023374767 countsByYear W20233747672017 @default.
- W2023374767 countsByYear W20233747672018 @default.
- W2023374767 countsByYear W20233747672019 @default.
- W2023374767 countsByYear W20233747672020 @default.
- W2023374767 countsByYear W20233747672021 @default.
- W2023374767 countsByYear W20233747672023 @default.
- W2023374767 crossrefType "journal-article" @default.
- W2023374767 hasAuthorship W2023374767A5011206616 @default.
- W2023374767 hasAuthorship W2023374767A5025250272 @default.
- W2023374767 hasAuthorship W2023374767A5041987246 @default.
- W2023374767 hasAuthorship W2023374767A5042005526 @default.
- W2023374767 hasAuthorship W2023374767A5043713924 @default.
- W2023374767 hasAuthorship W2023374767A5043985250 @default.
- W2023374767 hasAuthorship W2023374767A5047378476 @default.
- W2023374767 hasAuthorship W2023374767A5047383675 @default.
- W2023374767 hasAuthorship W2023374767A5051102321 @default.
- W2023374767 hasAuthorship W2023374767A5077061516 @default.
- W2023374767 hasAuthorship W2023374767A5077975999 @default.
- W2023374767 hasAuthorship W2023374767A5085954195 @default.
- W2023374767 hasAuthorship W2023374767A5089345009 @default.
- W2023374767 hasBestOaLocation W20233747672 @default.
- W2023374767 hasConcept C104317684 @default.
- W2023374767 hasConcept C105702510 @default.
- W2023374767 hasConcept C136834591 @default.
- W2023374767 hasConcept C169760540 @default.
- W2023374767 hasConcept C172680121 @default.
- W2023374767 hasConcept C25876315 @default.