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- W2023377029 abstract "Electrical field stimulation of the hamster, isolated vas deferens produces regular contractions that are unaffected by opioid-receptor agonists which are selective for the mu- or kappa-receptor types. However, agonists which show a selectivity for the delta-opioid receptor produce dose-related inhibitions of the stimulation-evoked contractions. Response of delta-opioid receptor agonists are antagonized in a competitive fashion by the selective delta-receptor antagonist ICI 174864, and also by naloxone. The kappa-opioid-agonist benzomorphans, bremazocine and ethylketocyclazocine are antagonists in the hamster vas deferens; bremazocine is particularly potent in this regard. In conclusion, the hamster, isolated vas deferens may contain only delta-opioid receptors and provides a simple and specific test for the assay of activity at the delta-opioid receptor." @default.
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- W2023377029 date "1984-12-01" @default.
- W2023377029 modified "2023-09-25" @default.
- W2023377029 title "Hamster vas deferens contains δ-opioid receptors" @default.
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- W2023377029 doi "https://doi.org/10.1016/0143-4179(84)90036-2" @default.
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