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• W2023378876 abstract "Previous studies have demonstrated that microdialysis is capable of detecting an abrupt and massive increase in extracellular K+ concentration ([K+]e) and a concomitant increase in extracellular concentration of excitatory amino acids (EAAs) during cerebral ischemia in the rat hippocampus in vivo. Following in situ administration of kynurenic acid (KYN), a broad-spectrum antagonist of EAAs, through the dialysis probe (5-10 mM), a delay in reaching the maximum level of increased [K+]e was observed in a dose-dependent manner. The initial component of the rapid increase in [K+]e appears to be mediated by EAAs released from nerve terminals." @default.
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• W2023378876 date "1991-12-01" @default.
• W2023378876 modified "2023-09-25" @default.
• W2023378876 title "Inhibition of rapid potassium flux during cerebral ischemia in vivo with an excitatory amino acid antagonist" @default.
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• W2023378876 doi "https://doi.org/10.1016/0006-8993(91)91412-t" @default.
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