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- W2023382095 abstract "Modifications of marcfortine A and paraherquamide A led to the discovery of 2-desoxoparaherquamide A (PNU-141962, 3) which is as active as paraherquamide A and has an improved safety profile. In order to do preclinical studies, we wished to synthesize isotope-labeled PNU-141962. This account will describe the synthesis of [CD3]-2-desoxoparaherquamide A (4). The deuterium product was prepared in anticipation of using a similar synthesis for the preparation of the corresponding 14C- and 3H-labeled products. Copyright © 2002 John Wiley & Sons, Ltd." @default.
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- W2023382095 date "2002-01-01" @default.
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- W2023382095 title "Isotopic labeling of 2-desoxoparaherquamide A (PNU-141962) with deuterium" @default.
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- W2023382095 doi "https://doi.org/10.1002/jlcr.624" @default.
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