Matches in SemOpenAlex for { <https://semopenalex.org/work/W2023385105> ?p ?o ?g. }
- W2023385105 endingPage "283" @default.
- W2023385105 startingPage "274" @default.
- W2023385105 abstract "PURPOSE: To compare the performance of radiologists and of a computer-aided detection (CAD) algorithm for pulmonary nodule detection on thin-section thoracic computed tomographic (CT) scans. MATERIALS AND METHODS: The study was approved by the institutional review board. The requirement of informed consent was waived. Twenty outpatients (age range, 15–91 years; mean, 64 years) were examined with chest CT (multi–detector row scanner, four detector rows, 1.25-mm section thickness, and 0.6-mm interval) for pulmonary nodules. Three radiologists independently analyzed CT scans, recorded the locus of each nodule candidate, and assigned each a confidence score. A CAD algorithm with parameters chosen by using cross validation was applied to the 20 scans. The reference standard was established by two experienced thoracic radiologists in consensus, with blind review of all nodule candidates and free search for additional nodules at a dedicated workstation for three-dimensional image analysis. True-positive (TP) and false-positive (FP) results and confidence levels were used to generate free-response receiver operating characteristic (ROC) plots. Double-reading performance was determined on the basis of TP detections by either reader. RESULTS: The 20 scans showed 195 noncalcified nodules with a diameter of 3 mm or more (reference reading). Area under the alternative free-response ROC curve was 0.54, 0.48, 0.55, and 0.36 for CAD and readers 1–3, respectively. Differences between reader 3 and CAD and between readers 2 and 3 were significant (P < .05); those between CAD and readers 1 and 2 were not significant. Mean sensitivity for individual readings was 50% (range, 41%–60%); double reading resulted in increase to 63% (range, 56%–67%). With CAD used at a threshold allowing only three FP detections per CT scan, mean sensitivity was increased to 76% (range, 73%–78%). CAD complemented individual readers by detecting additional nodules more effectively than did a second reader; CAD-reader weighted κ values were significantly lower than reader-reader weighted κ values (Wilcoxon rank sum test, P < .05). CONCLUSION: With CAD used at a level allowing only three FP detections per CT scan, sensitivity was substantially higher than with conventional double reading. Supplemental material: radiology.rsnajnls.org/cgi/content/full/2341040589/DC1 © RSNA, 2004" @default.
- W2023385105 created "2016-06-24" @default.
- W2023385105 creator A5018754537 @default.
- W2023385105 creator A5019381760 @default.
- W2023385105 creator A5020848541 @default.
- W2023385105 creator A5026726585 @default.
- W2023385105 creator A5029463759 @default.
- W2023385105 creator A5047022770 @default.
- W2023385105 creator A5051477797 @default.
- W2023385105 creator A5054691639 @default.
- W2023385105 creator A5056008709 @default.
- W2023385105 creator A5056555647 @default.
- W2023385105 creator A5091834429 @default.
- W2023385105 date "2005-01-01" @default.
- W2023385105 modified "2023-10-17" @default.
- W2023385105 title "Pulmonary Nodules on Multi–Detector Row CT Scans: Performance Comparison of Radiologists and Computer-aided Detection" @default.
- W2023385105 cites W1970089523 @default.
- W2023385105 cites W1978336831 @default.
- W2023385105 cites W1981227160 @default.
- W2023385105 cites W1988720696 @default.
- W2023385105 cites W2000401479 @default.
- W2023385105 cites W2001041155 @default.
- W2023385105 cites W2001434832 @default.
- W2023385105 cites W2002774010 @default.
- W2023385105 cites W2021955720 @default.
- W2023385105 cites W2030604164 @default.
- W2023385105 cites W2031827337 @default.
- W2023385105 cites W2031940570 @default.
- W2023385105 cites W2034215065 @default.
- W2023385105 cites W2035374697 @default.
- W2023385105 cites W2037711351 @default.
- W2023385105 cites W2054648089 @default.
- W2023385105 cites W2067798001 @default.
- W2023385105 cites W2071131529 @default.
- W2023385105 cites W2078003738 @default.
- W2023385105 cites W2083432437 @default.
- W2023385105 cites W2084127701 @default.
- W2023385105 cites W2084656440 @default.
- W2023385105 cites W2085652537 @default.
- W2023385105 cites W2089549968 @default.
- W2023385105 cites W2092897020 @default.
- W2023385105 cites W2094367903 @default.
- W2023385105 cites W2094769840 @default.
- W2023385105 cites W2095003563 @default.
- W2023385105 cites W2095485540 @default.
- W2023385105 cites W2098985260 @default.
- W2023385105 cites W2107083123 @default.
- W2023385105 cites W2108909227 @default.
- W2023385105 cites W2109711012 @default.
- W2023385105 cites W2109903408 @default.
- W2023385105 cites W2119793529 @default.
- W2023385105 cites W2124053461 @default.
- W2023385105 cites W2143045812 @default.
- W2023385105 cites W2152522287 @default.
- W2023385105 cites W2157574022 @default.
- W2023385105 cites W2200515657 @default.
- W2023385105 cites W4242137918 @default.
- W2023385105 cites W55053490 @default.
- W2023385105 doi "https://doi.org/10.1148/radiol.2341040589" @default.
- W2023385105 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/15537839" @default.
- W2023385105 hasPublicationYear "2005" @default.
- W2023385105 type Work @default.
- W2023385105 sameAs 2023385105 @default.
- W2023385105 citedByCount "244" @default.
- W2023385105 countsByYear W20233851052012 @default.
- W2023385105 countsByYear W20233851052013 @default.
- W2023385105 countsByYear W20233851052014 @default.
- W2023385105 countsByYear W20233851052015 @default.
- W2023385105 countsByYear W20233851052016 @default.
- W2023385105 countsByYear W20233851052017 @default.
- W2023385105 countsByYear W20233851052018 @default.
- W2023385105 countsByYear W20233851052019 @default.
- W2023385105 countsByYear W20233851052020 @default.
- W2023385105 countsByYear W20233851052021 @default.
- W2023385105 countsByYear W20233851052022 @default.
- W2023385105 countsByYear W20233851052023 @default.
- W2023385105 crossrefType "journal-article" @default.
- W2023385105 hasAuthorship W2023385105A5018754537 @default.
- W2023385105 hasAuthorship W2023385105A5019381760 @default.
- W2023385105 hasAuthorship W2023385105A5020848541 @default.
- W2023385105 hasAuthorship W2023385105A5026726585 @default.
- W2023385105 hasAuthorship W2023385105A5029463759 @default.
- W2023385105 hasAuthorship W2023385105A5047022770 @default.
- W2023385105 hasAuthorship W2023385105A5051477797 @default.
- W2023385105 hasAuthorship W2023385105A5054691639 @default.
- W2023385105 hasAuthorship W2023385105A5056008709 @default.
- W2023385105 hasAuthorship W2023385105A5056555647 @default.
- W2023385105 hasAuthorship W2023385105A5091834429 @default.
- W2023385105 hasConcept C126322002 @default.
- W2023385105 hasConcept C126838900 @default.
- W2023385105 hasConcept C127413603 @default.
- W2023385105 hasConcept C151730666 @default.
- W2023385105 hasConcept C154945302 @default.
- W2023385105 hasConcept C163716698 @default.
- W2023385105 hasConcept C194789388 @default.
- W2023385105 hasConcept C199639397 @default.
- W2023385105 hasConcept C2776731575 @default.
- W2023385105 hasConcept C2779751349 @default.