Matches in SemOpenAlex for { <https://semopenalex.org/work/W2023385495> ?p ?o ?g. }
Showing items 1 to 79 of
79
with 100 items per page.
- W2023385495 endingPage "289" @default.
- W2023385495 startingPage "287" @default.
- W2023385495 abstract "A first-derivative spectroscopic method for the simultaneous determination of bound and unbound drug in human serum and serum albumin solution was developed. As an example, the binding characteristics of rifampicin were studied. In serum albumin solution, the rifampicin bound and unbound fractions were determined at 473.5 and 475.8 nm, respectively. For human serum, the unbound fraction was determined at 479.4 nm. The results obtained by the first-derivative spectroscopic method were in agreement with those obtained by equilibrium dialysis. The proposed method is very simple and accurate when applied to measurements of drug:protein binding. Moreover, it allows a direct measurement of the bound and unbound forms without any physical separation." @default.
- W2023385495 created "2016-06-24" @default.
- W2023385495 creator A5008857086 @default.
- W2023385495 creator A5025426165 @default.
- W2023385495 creator A5025633228 @default.
- W2023385495 creator A5036246196 @default.
- W2023385495 creator A5054310827 @default.
- W2023385495 creator A5074795284 @default.
- W2023385495 date "1992-03-01" @default.
- W2023385495 modified "2023-09-26" @default.
- W2023385495 title "First-Derivative Spectroscopic Determination of Binding Characteristics of Rifampicin to Human Albumin and Serum" @default.
- W2023385495 cites W1980402363 @default.
- W2023385495 cites W2002700984 @default.
- W2023385495 cites W2009352732 @default.
- W2023385495 cites W2025761634 @default.
- W2023385495 cites W2087311350 @default.
- W2023385495 cites W2207375441 @default.
- W2023385495 doi "https://doi.org/10.1002/jps.2600810319" @default.
- W2023385495 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/1640369" @default.
- W2023385495 hasPublicationYear "1992" @default.
- W2023385495 type Work @default.
- W2023385495 sameAs 2023385495 @default.
- W2023385495 citedByCount "6" @default.
- W2023385495 countsByYear W20233854952020 @default.
- W2023385495 crossrefType "journal-article" @default.
- W2023385495 hasAuthorship W2023385495A5008857086 @default.
- W2023385495 hasAuthorship W2023385495A5025426165 @default.
- W2023385495 hasAuthorship W2023385495A5025633228 @default.
- W2023385495 hasAuthorship W2023385495A5036246196 @default.
- W2023385495 hasAuthorship W2023385495A5054310827 @default.
- W2023385495 hasAuthorship W2023385495A5074795284 @default.
- W2023385495 hasConcept C106159729 @default.
- W2023385495 hasConcept C111771559 @default.
- W2023385495 hasConcept C162324750 @default.
- W2023385495 hasConcept C165616093 @default.
- W2023385495 hasConcept C185592680 @default.
- W2023385495 hasConcept C2776125364 @default.
- W2023385495 hasConcept C2778597219 @default.
- W2023385495 hasConcept C2778607973 @default.
- W2023385495 hasConcept C2781233306 @default.
- W2023385495 hasConcept C43617362 @default.
- W2023385495 hasConcept C501593827 @default.
- W2023385495 hasConcept C51639874 @default.
- W2023385495 hasConcept C55493867 @default.
- W2023385495 hasConceptScore W2023385495C106159729 @default.
- W2023385495 hasConceptScore W2023385495C111771559 @default.
- W2023385495 hasConceptScore W2023385495C162324750 @default.
- W2023385495 hasConceptScore W2023385495C165616093 @default.
- W2023385495 hasConceptScore W2023385495C185592680 @default.
- W2023385495 hasConceptScore W2023385495C2776125364 @default.
- W2023385495 hasConceptScore W2023385495C2778597219 @default.
- W2023385495 hasConceptScore W2023385495C2778607973 @default.
- W2023385495 hasConceptScore W2023385495C2781233306 @default.
- W2023385495 hasConceptScore W2023385495C43617362 @default.
- W2023385495 hasConceptScore W2023385495C501593827 @default.
- W2023385495 hasConceptScore W2023385495C51639874 @default.
- W2023385495 hasConceptScore W2023385495C55493867 @default.
- W2023385495 hasIssue "3" @default.
- W2023385495 hasLocation W20233854951 @default.
- W2023385495 hasLocation W20233854952 @default.
- W2023385495 hasOpenAccess W2023385495 @default.
- W2023385495 hasPrimaryLocation W20233854951 @default.
- W2023385495 hasRelatedWork W1610318800 @default.
- W2023385495 hasRelatedWork W2023385495 @default.
- W2023385495 hasRelatedWork W2066017900 @default.
- W2023385495 hasRelatedWork W2073638061 @default.
- W2023385495 hasRelatedWork W2074491172 @default.
- W2023385495 hasRelatedWork W2080084127 @default.
- W2023385495 hasRelatedWork W2088060842 @default.
- W2023385495 hasRelatedWork W2127867331 @default.
- W2023385495 hasRelatedWork W2160907117 @default.
- W2023385495 hasRelatedWork W2162632962 @default.
- W2023385495 hasVolume "81" @default.
- W2023385495 isParatext "false" @default.
- W2023385495 isRetracted "false" @default.
- W2023385495 magId "2023385495" @default.
- W2023385495 workType "article" @default.