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- W2023385791 abstract "Abstract The rate of iodide uptake and formation of iodo-compounds in human leukocytes is regulated by adenosine 3′,5′-monophosphate (cyclic AMP). In the regulation to the dose, cyclic AMP decreases the iodine metabolism. Thyrotropin and prostaglandin E 1 increase cyclic AMP concentration in the human leukocytes. The rate of protein-bound iodine formation and total uptake of iodide by leukocytes depends on iodide concentration in the medium, that is optimal at 10 μ/100 ml. The conclusion is made, that the system adenyl cyclase-cyclic AMP response in the human leukocytes to thyrotropin, but in contrary to the thyroid gland, cyclic AMP depresses the rate of iodide metabolism." @default.
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- W2023385791 date "1972-04-01" @default.
- W2023385791 modified "2023-10-14" @default.
- W2023385791 title "Regulation of iodine metabolism in human leukocytes by adenosine 3′,5′-monophosphate" @default.
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- W2023385791 doi "https://doi.org/10.1016/0304-4165(72)90292-9" @default.
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