Matches in SemOpenAlex for { <https://semopenalex.org/work/W2023391098> ?p ?o ?g. }
Showing items 1 to 86 of
86
with 100 items per page.
- W2023391098 endingPage "423" @default.
- W2023391098 startingPage "418" @default.
- W2023391098 abstract "Cytokines play an integral role in the allergic response of the nasal mucosa. The ideal model for analysis of this interaction has yet to be perfected. We present a model for such evaluation and present results of experiments on the release of several cytokines. Freshly harvested human nasal turbinate mucosa was placed on a Gelfoam (Upjohn Co., Kalamazoo, Mich.) raft in a liquid medium to simulate the in situ environment. The allergic response was initiated by exposing the nasal mucosa to various combinations and amounts of human immunoglobulin E and antihuman immunoglobulin E antibody. The supernatants were collected and analyzed by enzyme-linked immunosorbent assay techniques for various cytokines. Histopathologic evaluation of the mucosa was performed throughout the exposure period, confirming normal cellular and tissue architecture and viability. This model was used to monitor the release of interleukin-3, granulocyte-macrophage colony-stimulating factor, tumor necrosis factor-alpha, and soluble tumor necrosis factor receptors after exposure to immunoglobulin E and immunoglobulin E antibody. Interleukin-3 did not show significant increases during the experiment testing period of 48 hours. Tumor necrosis factor-alpha and soluble tumor necrosis factor receptors demonstrated time-dependent increases in concentration after immunoglobulin E stimulation. Granulocyte-macrophage colony-stimulating factor showed the greatest time-dependent increases. Their impact on the understanding of the allergic response will be discussed." @default.
- W2023391098 created "2016-06-24" @default.
- W2023391098 creator A5079702700 @default.
- W2023391098 creator A5088373591 @default.
- W2023391098 creator A5088877512 @default.
- W2023391098 date "1996-03-01" @default.
- W2023391098 modified "2023-10-16" @default.
- W2023391098 title "Role of tumor necrosis factor and granulocyte-macrophage colony-stimulating factor in the late allergic response in human nasal mucosa" @default.
- W2023391098 cites W1497022815 @default.
- W2023391098 cites W1587557698 @default.
- W2023391098 cites W1967511024 @default.
- W2023391098 cites W1968240161 @default.
- W2023391098 cites W1979065191 @default.
- W2023391098 cites W1991312386 @default.
- W2023391098 cites W1995666918 @default.
- W2023391098 cites W2013396311 @default.
- W2023391098 cites W2021753844 @default.
- W2023391098 cites W2039274376 @default.
- W2023391098 cites W2056263350 @default.
- W2023391098 cites W2100994529 @default.
- W2023391098 cites W2101137099 @default.
- W2023391098 cites W2108006679 @default.
- W2023391098 cites W2133677681 @default.
- W2023391098 cites W2158139187 @default.
- W2023391098 doi "https://doi.org/10.1016/s0194-5998(96)70212-7" @default.
- W2023391098 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/8649876" @default.
- W2023391098 hasPublicationYear "1996" @default.
- W2023391098 type Work @default.
- W2023391098 sameAs 2023391098 @default.
- W2023391098 citedByCount "3" @default.
- W2023391098 crossrefType "journal-article" @default.
- W2023391098 hasAuthorship W2023391098A5079702700 @default.
- W2023391098 hasAuthorship W2023391098A5088373591 @default.
- W2023391098 hasAuthorship W2023391098A5088877512 @default.
- W2023391098 hasConcept C126322002 @default.
- W2023391098 hasConcept C141105273 @default.
- W2023391098 hasConcept C142724271 @default.
- W2023391098 hasConcept C159654299 @default.
- W2023391098 hasConcept C170493617 @default.
- W2023391098 hasConcept C17991360 @default.
- W2023391098 hasConcept C203014093 @default.
- W2023391098 hasConcept C2777478134 @default.
- W2023391098 hasConcept C2777983669 @default.
- W2023391098 hasConcept C2778690821 @default.
- W2023391098 hasConcept C2780898057 @default.
- W2023391098 hasConcept C503630168 @default.
- W2023391098 hasConcept C59377437 @default.
- W2023391098 hasConcept C71924100 @default.
- W2023391098 hasConcept C86803240 @default.
- W2023391098 hasConceptScore W2023391098C126322002 @default.
- W2023391098 hasConceptScore W2023391098C141105273 @default.
- W2023391098 hasConceptScore W2023391098C142724271 @default.
- W2023391098 hasConceptScore W2023391098C159654299 @default.
- W2023391098 hasConceptScore W2023391098C170493617 @default.
- W2023391098 hasConceptScore W2023391098C17991360 @default.
- W2023391098 hasConceptScore W2023391098C203014093 @default.
- W2023391098 hasConceptScore W2023391098C2777478134 @default.
- W2023391098 hasConceptScore W2023391098C2777983669 @default.
- W2023391098 hasConceptScore W2023391098C2778690821 @default.
- W2023391098 hasConceptScore W2023391098C2780898057 @default.
- W2023391098 hasConceptScore W2023391098C503630168 @default.
- W2023391098 hasConceptScore W2023391098C59377437 @default.
- W2023391098 hasConceptScore W2023391098C71924100 @default.
- W2023391098 hasConceptScore W2023391098C86803240 @default.
- W2023391098 hasIssue "3" @default.
- W2023391098 hasLocation W20233910981 @default.
- W2023391098 hasLocation W20233910982 @default.
- W2023391098 hasOpenAccess W2023391098 @default.
- W2023391098 hasPrimaryLocation W20233910981 @default.
- W2023391098 hasRelatedWork W1494014013 @default.
- W2023391098 hasRelatedWork W1529226217 @default.
- W2023391098 hasRelatedWork W2000901676 @default.
- W2023391098 hasRelatedWork W2035016769 @default.
- W2023391098 hasRelatedWork W2087982072 @default.
- W2023391098 hasRelatedWork W2111640883 @default.
- W2023391098 hasRelatedWork W2135420926 @default.
- W2023391098 hasRelatedWork W2156278784 @default.
- W2023391098 hasRelatedWork W2406266228 @default.
- W2023391098 hasRelatedWork W2774961326 @default.
- W2023391098 hasVolume "114" @default.
- W2023391098 isParatext "false" @default.
- W2023391098 isRetracted "false" @default.
- W2023391098 magId "2023391098" @default.
- W2023391098 workType "article" @default.