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- W2023391188 abstract "【目的】無症候性未破裂脳動脈瘤の治療前後における抑うつ症状の推移と，その高次脳機能に及ぼす影響について前方視的に検討した．【方法】2003年8月以降，天幕上アプローチを用いて直達手術を施行した無症候性未破裂脳動脈瘤の連続100例を対象とした．高次脳機能検査としてWAIS-Rと仮名ひろいテストを，抑うつ症状の評価でSelf-rating Depression Scale（SDS）を術前，術後2カ月と1年に行った．【結果】術後2カ月の転帰は97例でmRS 0であった．WAIS-Rのtotal IQと仮名ひろいテストの得点は，術後2カ月，1年ともに有意に増加していた．一方，SDSは術前・術後で変化を認めなかった．SDSと術後の高次脳機能の変化を解析すると，術前および術後8週で抑うつ状態の強い群で術後8週のWAIS-R total IQの低下が大きく，それぞれ負の相関があり有意であった．【結語】手術治療の高次脳機能に及ぼす影響は少ない．しかし術前や術後早期に抑うつ症状が強い場合，術後の高次脳機能に悪影響を与える．" @default.
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- W2023391188 date "2009-01-01" @default.
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- W2023391188 title "Alteration of peri-operative depression and its influence on cognitive function in patients with asymptomatic unruptured intracranial aneurysms" @default.
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