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- W2023392252 abstract "The chromosome of bacteriophage λ replicates in two stages. The first stage produces bidirectionally replicating theta-shaped intermediates (Schnös & Inman, 1970). This paper demonstrates that the late replicating intermediates of the second stage of replication are rolling circles, the intact forks of a majority of which progress from right to left and a minority progress in the other direction. The locations of the free ends of the tails of the rolling circles are variable with respect to the denaturation map of the chromosome. Furthermore, under the condition of limited replication, effected by partial suppression of amber mutants of the loci O and P, which specify the phage initiator proteins, rolling circles are also observed. A majority, but not all, of these rolling circles replicate from left to right." @default.
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- W2023392252 date "1975-10-01" @default.
- W2023392252 modified "2023-09-27" @default.
- W2023392252 title "Studies on the late replication of phage lambda: Rolling-circle replication of the wild type and a partially suppressed strain, Oam29 Pam80" @default.
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- W2023392252 doi "https://doi.org/10.1016/s0022-2836(75)80120-3" @default.
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