FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2023393544> ?p ?o ?g. }

• W2023393544 abstract "Effects of antibody feedback regulation on T helper (Th) cell functions required in plaque-forming cell (PFC) responses were studied in vitro. Using a sensitive functional assay, it was found that serum from immunized mice did not inhibit sheep erythrocyte (SRBC)-, or keyhole limpet hemocyanin-specific Th cell activation. SRBC-pulsed splenic adherent cells activated Th cells more efficiently when pulsed in the presence of anti-SRBC antiserum. PFC responses against, 2,4,6-trinitrophenyl (TNP) coupled to soluble carriers were studied under conditions in which linkage between hapten and the priming carrier was either required or not. Under both conditions, anti-carrier antiserum had an enhancing or no effect; only anti-hapten antiserum or monoclonal anti-hapten antibody were inhibitory. Thus, these results did show that antibody feedback was essentially hapten-specific and did not interfere with Th cell functions, except, possibly, that anti-hapten antibody interfered with linked cooperation at the level of hapten-B cell interaction, in addition to its inhibitory effect detectable under conditions of unlinked cooperation. Since SRBC-pulsed, adherent cells were very inefficient in stimulating anti-SRBC PFC responses, the results further suggested that phagocytosed antigen could only be recognized by Th cells but not by B cells. Finally, by attempting to further study hapten-B cell interactions, no PFC responses against TNP coupled to soluble carriers could be generated by substituting for Th cells with different types of secondary mixed leukocyte culture supernatant in cultures with pure surface Ig-positive cells. Only anti-SRBC PFC responses were generated in such cultures." @default.
• W2023393544 created "2016-06-24" @default.
• W2023393544 creator A5031931128 @default.
• W2023393544 date "1981-01-01" @default.
• W2023393544 modified "2023-10-14" @default.
• W2023393544 title "Antibody feedback regulationin vitro: T helper cell activation and T-B cell cooperation are not impaired by anti-carrier antibody" @default.
• W2023393544 cites W1964484350 @default.
• W2023393544 cites W1964532737 @default.
• W2023393544 cites W1967547442 @default.
• W2023393544 cites W1969397001 @default.
• W2023393544 cites W1984490106 @default.
• W2023393544 cites W1990237665 @default.
• W2023393544 cites W1990539976 @default.
• W2023393544 cites W1999258990 @default.
• W2023393544 cites W2008809605 @default.
• W2023393544 cites W2027540416 @default.
• W2023393544 cites W2040143846 @default.
• W2023393544 cites W2051189682 @default.
• W2023393544 cites W2051586885 @default.
• W2023393544 cites W2054860269 @default.
• W2023393544 cites W2055408664 @default.
• W2023393544 cites W2059943334 @default.
• W2023393544 cites W2063143669 @default.
• W2023393544 cites W2063496008 @default.
• W2023393544 cites W2071327217 @default.
• W2023393544 cites W2082059636 @default.
• W2023393544 cites W2096018584 @default.
• W2023393544 cites W2097191747 @default.
• W2023393544 cites W2105890426 @default.
• W2023393544 cites W2107128133 @default.
• W2023393544 cites W2124140989 @default.
• W2023393544 cites W2136612587 @default.
• W2023393544 cites W2141656073 @default.
• W2023393544 cites W2142492759 @default.
• W2023393544 cites W2146796146 @default.
• W2023393544 cites W2147833188 @default.
• W2023393544 cites W2148534815 @default.
• W2023393544 cites W2149068707 @default.
• W2023393544 cites W2149588832 @default.
• W2023393544 cites W2163097706 @default.
• W2023393544 cites W2480614086 @default.
• W2023393544 cites W294906880 @default.
• W2023393544 doi "https://doi.org/10.1002/eji.1830110710" @default.
• W2023393544 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/7026263" @default.
• W2023393544 hasPublicationYear "1981" @default.
• W2023393544 type Work @default.
• W2023393544 sameAs 2023393544 @default.
• W2023393544 citedByCount "10" @default.
• W2023393544 countsByYear W20233935442017 @default.
• W2023393544 crossrefType "journal-article" @default.
• W2023393544 hasAuthorship W2023393544A5031931128 @default.
• W2023393544 hasConcept C100701293 @default.
• W2023393544 hasConcept C147483822 @default.
• W2023393544 hasConcept C1491633281 @default.
• W2023393544 hasConcept C153911025 @default.
• W2023393544 hasConcept C159654299 @default.
• W2023393544 hasConcept C202751555 @default.
• W2023393544 hasConcept C203014093 @default.
• W2023393544 hasConcept C2776090121 @default.
• W2023393544 hasConcept C2778453870 @default.
• W2023393544 hasConcept C29144244 @default.
• W2023393544 hasConcept C55493867 @default.
• W2023393544 hasConcept C59822182 @default.
• W2023393544 hasConcept C81444415 @default.
• W2023393544 hasConcept C86803240 @default.
• W2023393544 hasConcept C8891405 @default.
• W2023393544 hasConcept C91523082 @default.
• W2023393544 hasConceptScore W2023393544C100701293 @default.
• W2023393544 hasConceptScore W2023393544C147483822 @default.
• W2023393544 hasConceptScore W2023393544C1491633281 @default.
• W2023393544 hasConceptScore W2023393544C153911025 @default.
• W2023393544 hasConceptScore W2023393544C159654299 @default.
• W2023393544 hasConceptScore W2023393544C202751555 @default.
• W2023393544 hasConceptScore W2023393544C203014093 @default.
• W2023393544 hasConceptScore W2023393544C2776090121 @default.
• W2023393544 hasConceptScore W2023393544C2778453870 @default.
• W2023393544 hasConceptScore W2023393544C29144244 @default.
• W2023393544 hasConceptScore W2023393544C55493867 @default.
• W2023393544 hasConceptScore W2023393544C59822182 @default.
• W2023393544 hasConceptScore W2023393544C81444415 @default.
• W2023393544 hasConceptScore W2023393544C86803240 @default.
• W2023393544 hasConceptScore W2023393544C8891405 @default.
• W2023393544 hasConceptScore W2023393544C91523082 @default.
• W2023393544 hasLocation W20233935441 @default.
• W2023393544 hasLocation W20233935442 @default.
• W2023393544 hasOpenAccess W2023393544 @default.
• W2023393544 hasPrimaryLocation W20233935441 @default.
• W2023393544 hasRelatedWork W1487951021 @default.
• W2023393544 hasRelatedWork W1513530335 @default.
• W2023393544 hasRelatedWork W1571316787 @default.
• W2023393544 hasRelatedWork W1573713772 @default.
• W2023393544 hasRelatedWork W1589286368 @default.
• W2023393544 hasRelatedWork W1973692620 @default.
• W2023393544 hasRelatedWork W1986664592 @default.
• W2023393544 hasRelatedWork W2023393544 @default.
• W2023393544 hasRelatedWork W2072095179 @default.
• W2023393544 hasRelatedWork W2411451838 @default.
• W2023393544 isParatext "false" @default.
• W2023393544 isRetracted "false" @default.
• W2023393544 magId "2023393544" @default.

• next