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- W2023394168 abstract "Abstract It has been demonstrated that solutions of 1% concentrated hydrochloric acid in methanol may become oxidising when exposed to light and air. Addition of such solutions to butyl chloride extracts of drugs from blood or aqueous standards can seriously lower the yields obtained. This is particularly so for chlorpromazine although all three other drugs tried, amitriptyline, codeine and methadone, were also affected. Storage of the reagent, used to stabilize basic drugs during concentration of extracts, should be for periods of less than 4 weeks, and in brown bottles." @default.
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- W2023394168 date "1982-07-01" @default.
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- W2023394168 title "Decreases in Yields of Extracted Drugs After Exposure to 1% Hydrochloric Acid in Methanol" @default.
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- W2023394168 doi "https://doi.org/10.1016/s0015-7368(82)71495-1" @default.
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