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- W2023394518 abstract "1. The metabolic fate of the insoluble bile acid sequestrant polidexide, (poly-[2-(diethylamino)ethyl] polyglycerylenedextran hydrochloride), was studied in four adult humans following the oral administration of the 14C-labelled substance. 2. The mean cumulative recovery of 14C in faeces was 95·3% (s.e.m. = 1·1) of the administered dose, while mean cumulative recovery in urine was 0·37% (s.e.m. = 0·13) of the oral dose. 3. Only background levels of radioactivity were detectable in plasma samples taken 1·3 days after administration of tracer. 4. The findings suggested that polidexide was not absorbed from the gastrointestinal tract in man to any significant degree." @default.
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- W2023394518 date "1976-02-01" @default.
- W2023394518 modified "2023-09-27" @default.
- W2023394518 title "THE FATE OF THE ORALLY ADMINISTERED BILE ACID SEQUESTRANT, POLIDEXIDE, IN HUMANS" @default.
- W2023394518 cites W2067872517 @default.
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- W2023394518 doi "https://doi.org/10.1111/j.1440-1681.1976.tb00595.x" @default.
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