FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2023395324> ?p ?o ?g. }

• W2023395324 endingPage "1836" @default.
• W2023395324 startingPage "1829" @default.
• W2023395324 abstract "Chemokine-like factor (CKLF)-like MARVEL transmembrane domain-containing 1 (CMTM1) consists of at least 23 alternatively spliced isoforms designated CMTM1_v1-v23. In the present study, we detected CMTM1_v17 expression in multiple human normal and tumor tissues and found that CMTM1_v17 was highly expressed in testis and many tumor tissues including breast tumor. The overexpression of CMTM1_v17 in the breast cancer cell line MDA-MB-231 promoted cell proliferation and resistance to tumor necrosis factor-α (TNF-α)-induced apoptosis. Moreover, siRNA-mediated silencing of CMTM1_v17 sensitized MDA-MB-231 cells to TNF-α-induced apoptosis. We propose that CMTM1_v17 may be a novel potential target for therapy in breast cancer patients. The present study provides insight into a novel mechanism by which CMTM1_v17 enhances cellular proliferation and abrogates TNF-α-induced apoptosis. These findings also have implications for clinical practice as they highlight the potential for therapeutic targeting of CMTM1_v17 for the treatment of breast and other cancers in which CMTM1_v17 impacts cellular proliferation and survival." @default.
• W2023395324 created "2016-06-24" @default.
• W2023395324 creator A5016770104 @default.
• W2023395324 creator A5029484872 @default.
• W2023395324 creator A5037677450 @default.
• W2023395324 creator A5041638115 @default.
• W2023395324 creator A5053643944 @default.
• W2023395324 creator A5065560361 @default.
• W2023395324 creator A5077375966 @default.
• W2023395324 creator A5081946864 @default.
• W2023395324 date "2014-08-20" @default.
• W2023395324 modified "2023-09-30" @default.
• W2023395324 title "CMTM1_v17 is a novel potential therapeutic target in breast cancer" @default.
• W2023395324 cites W1531083195 @default.
• W2023395324 cites W1545261708 @default.
• W2023395324 cites W1998450591 @default.
• W2023395324 cites W2001056353 @default.
• W2023395324 cites W2042337852 @default.
• W2023395324 cites W2047734731 @default.
• W2023395324 cites W2048965563 @default.
• W2023395324 cites W2062254328 @default.
• W2023395324 cites W2072380594 @default.
• W2023395324 cites W2078050621 @default.
• W2023395324 cites W2118143278 @default.
• W2023395324 cites W2120735394 @default.
• W2023395324 cites W2129964802 @default.
• W2023395324 cites W2139677024 @default.
• W2023395324 cites W2155758159 @default.
• W2023395324 cites W4244985774 @default.
• W2023395324 doi "https://doi.org/10.3892/or.2014.3429" @default.
• W2023395324 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/25175386" @default.
• W2023395324 hasPublicationYear "2014" @default.
• W2023395324 type Work @default.
• W2023395324 sameAs 2023395324 @default.
• W2023395324 citedByCount "16" @default.
• W2023395324 countsByYear W20233953242017 @default.
• W2023395324 countsByYear W20233953242019 @default.
• W2023395324 countsByYear W20233953242020 @default.
• W2023395324 countsByYear W20233953242021 @default.
• W2023395324 countsByYear W20233953242022 @default.
• W2023395324 countsByYear W20233953242023 @default.
• W2023395324 crossrefType "journal-article" @default.
• W2023395324 hasAuthorship W2023395324A5016770104 @default.
• W2023395324 hasAuthorship W2023395324A5029484872 @default.
• W2023395324 hasAuthorship W2023395324A5037677450 @default.
• W2023395324 hasAuthorship W2023395324A5041638115 @default.
• W2023395324 hasAuthorship W2023395324A5053643944 @default.
• W2023395324 hasAuthorship W2023395324A5065560361 @default.
• W2023395324 hasAuthorship W2023395324A5077375966 @default.
• W2023395324 hasAuthorship W2023395324A5081946864 @default.
• W2023395324 hasBestOaLocation W20233953241 @default.
• W2023395324 hasConcept C104317684 @default.
• W2023395324 hasConcept C119056186 @default.
• W2023395324 hasConcept C121608353 @default.
• W2023395324 hasConcept C17991360 @default.
• W2023395324 hasConcept C190283241 @default.
• W2023395324 hasConcept C203014093 @default.
• W2023395324 hasConcept C2781018059 @default.
• W2023395324 hasConcept C29537977 @default.
• W2023395324 hasConcept C502942594 @default.
• W2023395324 hasConcept C530470458 @default.
• W2023395324 hasConcept C54355233 @default.
• W2023395324 hasConcept C55493867 @default.
• W2023395324 hasConcept C62112901 @default.
• W2023395324 hasConcept C86803240 @default.
• W2023395324 hasConceptScore W2023395324C104317684 @default.
• W2023395324 hasConceptScore W2023395324C119056186 @default.
• W2023395324 hasConceptScore W2023395324C121608353 @default.
• W2023395324 hasConceptScore W2023395324C17991360 @default.
• W2023395324 hasConceptScore W2023395324C190283241 @default.
• W2023395324 hasConceptScore W2023395324C203014093 @default.
• W2023395324 hasConceptScore W2023395324C2781018059 @default.
• W2023395324 hasConceptScore W2023395324C29537977 @default.
• W2023395324 hasConceptScore W2023395324C502942594 @default.
• W2023395324 hasConceptScore W2023395324C530470458 @default.
• W2023395324 hasConceptScore W2023395324C54355233 @default.
• W2023395324 hasConceptScore W2023395324C55493867 @default.
• W2023395324 hasConceptScore W2023395324C62112901 @default.
• W2023395324 hasConceptScore W2023395324C86803240 @default.
• W2023395324 hasIssue "5" @default.
• W2023395324 hasLocation W20233953241 @default.
• W2023395324 hasLocation W20233953242 @default.
• W2023395324 hasOpenAccess W2023395324 @default.
• W2023395324 hasPrimaryLocation W20233953241 @default.
• W2023395324 hasRelatedWork W2042520059 @default.
• W2023395324 hasRelatedWork W2063065382 @default.
• W2023395324 hasRelatedWork W2117441185 @default.
• W2023395324 hasRelatedWork W2159406762 @default.
• W2023395324 hasRelatedWork W2265311593 @default.
• W2023395324 hasRelatedWork W2348417465 @default.
• W2023395324 hasRelatedWork W2600552753 @default.
• W2023395324 hasRelatedWork W2772993264 @default.
• W2023395324 hasRelatedWork W3045868324 @default.
• W2023395324 hasRelatedWork W4383711253 @default.
• W2023395324 hasVolume "32" @default.
• W2023395324 isParatext "false" @default.
• W2023395324 isRetracted "false" @default.
• W2023395324 magId "2023395324" @default.

• next