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- W2023396198 abstract "Abstract. DHEA sulphate was administered orally in doses of 20 to 80 mg to 13 subjects with hypercholesterolaemia or hyperlipaemia. Plasma lipid and neutral steroid sulphate levels as well as the excretion of individual ll-deoxy-17-ketosteroids and estrogens in urine were investigated before and during the treatment. No effect was observed on plasma free or esterified cholesterol, on total or individual phospholipid values, or on routine blood haematological or chemical analyses. However, the plasma C19 steroid sulphate levels increased considerably as well as the urinary excretion of the 11-deoxy-17-keto-steroids, indicating good absorption of the compound administered. No significant changes in estrogen excretion following DHEA sulphate treatment could be noted. —When 13 male subjects with hypercholesterolaemia and hyperlipaemia were compared with 42 normal controls of the same mean age, a significantly lower urinary excretion of dehydroepiandrosterone and estrone as well as of estrone + estradiol was observed in the pathological series." @default.
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- W2023396198 date "1972-04-01" @default.
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- W2023396198 title "Plasma Lipids and Steroid Hormones in Patients with Hypercholesterolaemia or Hyperlipaemia during Dehydroepiandrosterone Sulphate Administration" @default.
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- W2023396198 doi "https://doi.org/10.1111/j.1365-2362.1972.tb00575.x" @default.
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