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- W2023397668 abstract "In mouse mammary epithelial cells in primary culture, mechanical stimulation of a cell induced in other cells within the same colony a short depolarization of less than 15 mV with a duration of 1-8 s and a subsequent, prominent hyperpolarization of 6 mV lasting 10-40 s. Epidermal growth factor induces a spontaneous hyperpolarizing response in cultured mammary cells, and in cells treated with EGF mechanical stimulation produced a greater hyperpolarization, while the amplitude of the depolarizing response was not affected. The amplitude of the mechanically induced hyperpolarization was markedly reduced by quinine and tetraethylammonium, blockers of the Ca2+ -dependent K+ channel. The results suggest that the Ca2+ -dependent K+ channel was involved in the hyperpolarization." @default.
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- W2023397668 date "1987-10-19" @default.
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- W2023397668 title "Mechanically induced electrical responses in murine mammary epithelial cells in primary culture" @default.
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- W2023397668 doi "https://doi.org/10.1016/0014-5793(87)80514-8" @default.
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