FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2023401728> ?p ?o ?g. }

• W2023401728 endingPage "653" @default.
• W2023401728 startingPage "643" @default.
• W2023401728 abstract "Apoptosis is necessary for the regulation of growth during development, but the precise details of this regulation have not been completely characterized. In this study, we used the Drosophila genital disc as a model to analyze the contribution of apoptosis to growth regulation. We studied the expression or activity of several elements of the apoptotic death pathway such as Drosophila inhibitor of apoptosis1, caspases, the apoptotic genes reaper (rpr) and head involution defective, as well as elements of the Jun-NH2-terminal kinase (JNK) pathway. We found that the JNK pathway is active in a dynamic, asymmetric and genitalia-specific manner. Apoptosis, as measured in terms of the expression of a variety of apoptotic molecules, occurs in a JNK-dependent and -independent manner and was detected among engrailed (en) expressing cells. JNK regulation of apoptotic genes is necessary to control growth in both sexes and rotation in males; this regulatory role is necessary to execute en(+) cell death and to activate expression of rpr in these cells. rpr is up-regulated at antero-posterior borders, and this expression appears to be of particular importance in the control of growth, since the balance between cell proliferation and death in those regions appears to depend on the equilibrium between pro- and anti-apoptotic factors at a cellular level." @default.
• W2023401728 created "2016-06-24" @default.
• W2023401728 creator A5000387353 @default.
• W2023401728 creator A5025480242 @default.
• W2023401728 creator A5062151462 @default.
• W2023401728 creator A5070840083 @default.
• W2023401728 date "2010-01-01" @default.
• W2023401728 modified "2023-10-03" @default.
• W2023401728 title "Both jnk and apoptosis pathways regulate growth and terminalia rotation during Drosophila genital disc development" @default.
• W2023401728 cites W1543220037 @default.
• W2023401728 cites W1565254539 @default.
• W2023401728 cites W1938687318 @default.
• W2023401728 cites W1982124131 @default.
• W2023401728 cites W1989723819 @default.
• W2023401728 cites W1990248374 @default.
• W2023401728 cites W1997663906 @default.
• W2023401728 cites W2003769148 @default.
• W2023401728 cites W2011868306 @default.
• W2023401728 cites W2015588789 @default.
• W2023401728 cites W2018761778 @default.
• W2023401728 cites W2020020471 @default.
• W2023401728 cites W2023153839 @default.
• W2023401728 cites W2036212571 @default.
• W2023401728 cites W2041629876 @default.
• W2023401728 cites W2050533433 @default.
• W2023401728 cites W2053277135 @default.
• W2023401728 cites W2055927824 @default.
• W2023401728 cites W2062469875 @default.
• W2023401728 cites W2078144681 @default.
• W2023401728 cites W2081092282 @default.
• W2023401728 cites W2106966818 @default.
• W2023401728 cites W2110643873 @default.
• W2023401728 cites W2115485398 @default.
• W2023401728 cites W2115646229 @default.
• W2023401728 cites W2118609604 @default.
• W2023401728 cites W2127328369 @default.
• W2023401728 cites W2138519364 @default.
• W2023401728 cites W2139587743 @default.
• W2023401728 cites W2140955159 @default.
• W2023401728 cites W2154903535 @default.
• W2023401728 cites W2155309157 @default.
• W2023401728 cites W2155767924 @default.
• W2023401728 cites W2157879099 @default.
• W2023401728 cites W2158225837 @default.
• W2023401728 cites W2164293876 @default.
• W2023401728 cites W2167234212 @default.
• W2023401728 cites W2169744093 @default.
• W2023401728 cites W2171572099 @default.
• W2023401728 cites W2171784464 @default.
• W2023401728 cites W2184390227 @default.
• W2023401728 cites W52444691 @default.
• W2023401728 doi "https://doi.org/10.1387/ijdb.082724sb" @default.
• W2023401728 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/20209437" @default.
• W2023401728 hasPublicationYear "2010" @default.
• W2023401728 type Work @default.
• W2023401728 sameAs 2023401728 @default.
• W2023401728 citedByCount "13" @default.
• W2023401728 countsByYear W20234017282012 @default.
• W2023401728 countsByYear W20234017282015 @default.
• W2023401728 countsByYear W20234017282017 @default.
• W2023401728 countsByYear W20234017282019 @default.
• W2023401728 countsByYear W20234017282020 @default.
• W2023401728 countsByYear W20234017282021 @default.
• W2023401728 countsByYear W20234017282022 @default.
• W2023401728 crossrefType "journal-article" @default.
• W2023401728 hasAuthorship W2023401728A5000387353 @default.
• W2023401728 hasAuthorship W2023401728A5025480242 @default.
• W2023401728 hasAuthorship W2023401728A5062151462 @default.
• W2023401728 hasAuthorship W2023401728A5070840083 @default.
• W2023401728 hasBestOaLocation W20234017281 @default.
• W2023401728 hasConcept C104317684 @default.
• W2023401728 hasConcept C121587040 @default.
• W2023401728 hasConcept C169760540 @default.
• W2023401728 hasConcept C184235292 @default.
• W2023401728 hasConcept C186720457 @default.
• W2023401728 hasConcept C190283241 @default.
• W2023401728 hasConcept C2780104201 @default.
• W2023401728 hasConcept C2781409172 @default.
• W2023401728 hasConcept C31573885 @default.
• W2023401728 hasConcept C54355233 @default.
• W2023401728 hasConcept C62112901 @default.
• W2023401728 hasConcept C62478195 @default.
• W2023401728 hasConcept C64632358 @default.
• W2023401728 hasConcept C86339819 @default.
• W2023401728 hasConcept C86803240 @default.
• W2023401728 hasConcept C91986751 @default.
• W2023401728 hasConcept C95444343 @default.
• W2023401728 hasConcept C98424977 @default.
• W2023401728 hasConceptScore W2023401728C104317684 @default.
• W2023401728 hasConceptScore W2023401728C121587040 @default.
• W2023401728 hasConceptScore W2023401728C169760540 @default.
• W2023401728 hasConceptScore W2023401728C184235292 @default.
• W2023401728 hasConceptScore W2023401728C186720457 @default.
• W2023401728 hasConceptScore W2023401728C190283241 @default.
• W2023401728 hasConceptScore W2023401728C2780104201 @default.
• W2023401728 hasConceptScore W2023401728C2781409172 @default.
• W2023401728 hasConceptScore W2023401728C31573885 @default.
• W2023401728 hasConceptScore W2023401728C54355233 @default.

• next