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- W2023403129 abstract "To identify nerve growth factor (NGF) target cells in normal and pathologic human lymphoid tissues, we have studied the expression of the low-affinity NGF receptor (p75LNGFR) and the high-affinity tropomyosin-related kinase NGF receptor (TrkA). A RNAse protection assay revealed the expression of trk transcripts in thymus, spleen, palatine tonsils and lymph nodes. TrkA immunoreactivity was shown in thymic epithelial cells, cryptic tonsillar epithelium and several monocyte-derived cells including epithelioid and multinucleated Langhans' cells, follicular dendritic cells and interdigitated reticular cells. TrkA immunoreactivity was rarely observed in normal T- and B-lymphocytes, but was intense in lymphoma cells of several B-cell lymphoma subtypes, anaplastic large cell lymphomas and Reed–Sternberg cells. Western blot analysis revealed the presence of p75LNGFR and of p80Trk and glycosylated Trk isoforms (gp110, gp140). p75LNGFR immunoreactivity was detected in epithelial Hassal's bodies, follicular dendritic cells, interdigitated reticular cells, periarteriolar macrophages, endothelial sinusal cells and nerve endings. The broad expression of NGF receptors may be an indicator of neurotrophin activity in lymphoid tissues and suggests their implication in inflammatory or lymphoproliferative disorders." @default.
- W2023403129 created "2016-06-24" @default.
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- W2023403129 date "1997-08-01" @default.
- W2023403129 modified "2023-10-18" @default.
- W2023403129 title "Distribution of NGF receptors in normal and pathologic human lymphoid tissues" @default.
- W2023403129 cites W1527035699 @default.
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- W2023403129 cites W1576690422 @default.
- W2023403129 cites W1577472511 @default.
- W2023403129 cites W1584113679 @default.
- W2023403129 cites W1741848512 @default.
- W2023403129 cites W1863695472 @default.
- W2023403129 cites W1901043290 @default.
- W2023403129 cites W1913583396 @default.
- W2023403129 cites W1965779217 @default.
- W2023403129 cites W1965824265 @default.
- W2023403129 cites W1966734514 @default.
- W2023403129 cites W1979241752 @default.
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- W2023403129 cites W1982780398 @default.
- W2023403129 cites W1986841583 @default.
- W2023403129 cites W198779817 @default.
- W2023403129 cites W1989588869 @default.
- W2023403129 cites W1990073151 @default.
- W2023403129 cites W1993713261 @default.
- W2023403129 cites W1994721743 @default.
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- W2023403129 cites W2000079550 @default.
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- W2023403129 cites W2033727409 @default.
- W2023403129 cites W2037831105 @default.
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- W2023403129 doi "https://doi.org/10.1016/s0165-5728(97)00055-6" @default.
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