Matches in SemOpenAlex for { <https://semopenalex.org/work/W2023404479> ?p ?o ?g. }
Showing items 1 to 88 of
88
with 100 items per page.
- W2023404479 endingPage "170" @default.
- W2023404479 startingPage "167" @default.
- W2023404479 abstract "The observation that long-standing hyperuricemia is associated with chronic tubulointerstitial disease, afferent arteriolopathy, intrarenal vasoconstriction, and increased vascular resistance raises the hypothesis that hyperuricemia might contribute to chronic cyclosporine (CsA) nephropathy. The aim of the present study was to investigate the effect of hyperuricemia on chronic CsA nephropathy.Patients who were treated with CsA-based immunsuppressive regimens and underwent a renal biopsy were enrolled in this case-control study. We retrospectively obtained posttransplant baseline serum creatinine, uric acid (UA), mean serum UA, and creatinine values 3 months prior to biopsy. CsA trough levels, mean blood pressure, diuretic and antihypertensive treatment were recorded. Biopsy specimens showing CsA nephropathy (n = 34) were revaluated by a pathologist to score CsA nephropathy according to recent quantitative criteria for calcineurin inhibitor arteriolopathy as proposed by M.J. Mihatsch.As compared with the non-CsA nephropathy group, recipient and donor ages, donor origin and cold ischemia times were similar for the CsA nephropathy group (P > .05). Mean CsA doses, CsA trough (C(0)), and C(2) levels were not different between the groups (P > .05). Systolic and diastolic blood pressure, glomerular filtration rate, diuretic usage, and antihypertensive treatment were also similar in CsA nephropathy and non-CsA nephropathy groups (P > .05). Mean serum UA level within 3 months prior to biopsy in the CsA nephropathy and non-CsA nephropathy groups were 7.5 +/- 1.4 mg/dL versus 5.7 +/- 1.4 mg/dL, respectively (P < .001).Hyperuricemia seems to exacerbate CsA-induced nephropathy." @default.
- W2023404479 created "2016-06-24" @default.
- W2023404479 creator A5006387352 @default.
- W2023404479 creator A5024639284 @default.
- W2023404479 creator A5030231071 @default.
- W2023404479 creator A5040576955 @default.
- W2023404479 creator A5043900005 @default.
- W2023404479 creator A5051261613 @default.
- W2023404479 creator A5061006683 @default.
- W2023404479 date "2008-01-01" @default.
- W2023404479 modified "2023-10-18" @default.
- W2023404479 title "Hyperuricemia Influences Chronic Cyclosporine Nephropathy" @default.
- W2023404479 cites W1806693387 @default.
- W2023404479 cites W2004352058 @default.
- W2023404479 cites W2039579782 @default.
- W2023404479 cites W2043172105 @default.
- W2023404479 cites W2047916120 @default.
- W2023404479 cites W2136728326 @default.
- W2023404479 cites W2148296899 @default.
- W2023404479 doi "https://doi.org/10.1016/j.transproceed.2007.11.013" @default.
- W2023404479 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/18261576" @default.
- W2023404479 hasPublicationYear "2008" @default.
- W2023404479 type Work @default.
- W2023404479 sameAs 2023404479 @default.
- W2023404479 citedByCount "9" @default.
- W2023404479 countsByYear W20234044792012 @default.
- W2023404479 countsByYear W20234044792014 @default.
- W2023404479 countsByYear W20234044792015 @default.
- W2023404479 crossrefType "journal-article" @default.
- W2023404479 hasAuthorship W2023404479A5006387352 @default.
- W2023404479 hasAuthorship W2023404479A5024639284 @default.
- W2023404479 hasAuthorship W2023404479A5030231071 @default.
- W2023404479 hasAuthorship W2023404479A5040576955 @default.
- W2023404479 hasAuthorship W2023404479A5043900005 @default.
- W2023404479 hasAuthorship W2023404479A5051261613 @default.
- W2023404479 hasAuthorship W2023404479A5061006683 @default.
- W2023404479 hasConcept C126322002 @default.
- W2023404479 hasConcept C126894567 @default.
- W2023404479 hasConcept C134018914 @default.
- W2023404479 hasConcept C159641895 @default.
- W2023404479 hasConcept C2778653478 @default.
- W2023404479 hasConcept C2779458710 @default.
- W2023404479 hasConcept C2779721657 @default.
- W2023404479 hasConcept C2779881121 @default.
- W2023404479 hasConcept C2780306776 @default.
- W2023404479 hasConcept C2781087799 @default.
- W2023404479 hasConcept C2781184683 @default.
- W2023404479 hasConcept C555293320 @default.
- W2023404479 hasConcept C71924100 @default.
- W2023404479 hasConcept C84393581 @default.
- W2023404479 hasConcept C90924648 @default.
- W2023404479 hasConceptScore W2023404479C126322002 @default.
- W2023404479 hasConceptScore W2023404479C126894567 @default.
- W2023404479 hasConceptScore W2023404479C134018914 @default.
- W2023404479 hasConceptScore W2023404479C159641895 @default.
- W2023404479 hasConceptScore W2023404479C2778653478 @default.
- W2023404479 hasConceptScore W2023404479C2779458710 @default.
- W2023404479 hasConceptScore W2023404479C2779721657 @default.
- W2023404479 hasConceptScore W2023404479C2779881121 @default.
- W2023404479 hasConceptScore W2023404479C2780306776 @default.
- W2023404479 hasConceptScore W2023404479C2781087799 @default.
- W2023404479 hasConceptScore W2023404479C2781184683 @default.
- W2023404479 hasConceptScore W2023404479C555293320 @default.
- W2023404479 hasConceptScore W2023404479C71924100 @default.
- W2023404479 hasConceptScore W2023404479C84393581 @default.
- W2023404479 hasConceptScore W2023404479C90924648 @default.
- W2023404479 hasIssue "1" @default.
- W2023404479 hasLocation W20234044791 @default.
- W2023404479 hasLocation W20234044792 @default.
- W2023404479 hasOpenAccess W2023404479 @default.
- W2023404479 hasPrimaryLocation W20234044791 @default.
- W2023404479 hasRelatedWork W1503738388 @default.
- W2023404479 hasRelatedWork W2124543160 @default.
- W2023404479 hasRelatedWork W2156997248 @default.
- W2023404479 hasRelatedWork W2370453960 @default.
- W2023404479 hasRelatedWork W2415262299 @default.
- W2023404479 hasRelatedWork W2586983423 @default.
- W2023404479 hasRelatedWork W2989095099 @default.
- W2023404479 hasRelatedWork W3011378569 @default.
- W2023404479 hasRelatedWork W3133946270 @default.
- W2023404479 hasRelatedWork W2309419860 @default.
- W2023404479 hasVolume "40" @default.
- W2023404479 isParatext "false" @default.
- W2023404479 isRetracted "false" @default.
- W2023404479 magId "2023404479" @default.
- W2023404479 workType "article" @default.