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• W2023405712 abstract "Blood insulin levels in obese subjects with high blood pressure (BP) are higher than normal and are associated with changes in fats metabolism. Subjects with high blood pressure show primary insulin resistance and their blood insulin values show variations according to the severity of hypertension. Forty subjects aged between 20 and 45 years were selected by means of inquiry to detect cardiovascular risk factors among workers of the General Maintenance Service of the Central University of Venezuela (UCV). The study group was classified as obese with or without high blood pressure (n=28) and compared with the group control (n=12). The different methods for determination of blood insulin levels were applied to each of the study groups, to compare the values of glucose and insulin in a group of obese subjects with or without hypertension, with the group control, as well as to compare the different ways of determination, to establish correlation between blood insulin values in each group and anthropometrics, blood pressure values and fats metabolism. The most important findings in our study were as follows: higher values for fasting blood sugar and insulin in obese subjects, independent of presence or absence of hypertension. Blood insulin post-stimulation was greater in obese and hypertensive subjects. The ratio insulin/glucose (R I/G), also called insulinogenic index, was normal but was significantly higher when compared with those of the group control, and the same applies to the corrected insulin/glucose ratio (I/G Rc). Direct correlation was found between insulin and blood pressure values when compared with post-stimulation insulin values, but there was no correlation with diastolic BP values. According to our results, we deduce that our obese subjects behave as hyperinsulinemic after stimulation, but we could not conclude if insulin blood levels are associated with hypertension. Groups of obese subjects with or without high BP showed high values of blood cholesterol and triglycerides, lower HDL-C and normal LDL-C. We could conclude that obese subjects with or without hypertension behave as hyperinsulinemic, suggesting the possibility of insulin resistance." @default.
• W2023405712 created "2016-06-24" @default.
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• W2023405712 date "2002-07-01" @default.
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• W2023405712 title "Insulinemia: relation with obesity and high blood pressure" @default.
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• W2023405712 doi "https://doi.org/10.1016/s0531-5131(01)00581-7" @default.
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