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• W2023407920 abstract "The surface properties of titanium alloy implants for improved osseointegration in orthopaedic and dental surgery have been modified by many technologies. Hydroxyapatite coatings with a facultative integration of growth factors deposited by plasma spraying showed improved osseointegration. Our approach in order to enhance osseointegration was carried out by a surface modification method of titanium alloy implants called plasma chemical oxidation (PCO). PCO is an electrochemical procedure that converts the nm-thin natural occurring titanium-oxide layer on an implant to a 5 µm thick ceramic coating (TiOB-surface). Bioactive TiOB-surfaces have a porous microstructure and were loaded with calcium and phosphorous, while bioinert TiOB-surfaces with less calcium and phosphorous loadings are smooth. A rat tibial model with bilateral placement of titanium alloy implants was employed to analyze the bone response to TiOB-surfaces in vivo. 64 rats were randomly assigned to four groups of implants: (i) pure titanium alloy (control), ii) titanium alloy, type III anodization, (iii) bioinert TiOB-surface, and (iv) bioactive TiOB-surface. Mechanical fixation was evaluated by pull out tests at 3 and 8 weeks.The bioactive TiOB-surface showed significantly increased shear strength at 8 weeks compared to all other groups." @default.
• W2023407920 created "2016-06-24" @default.
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• W2023407920 date "2011-10-18" @default.
• W2023407920 modified "2023-09-29" @default.
• W2023407920 title "Bioactive TiOB-Coating on Titanium Alloy Implants Enhances Osseointegration in a Rat Model" @default.
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• W2023407920 doi "https://doi.org/10.1002/adem.201180032" @default.
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