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- W2023408367 abstract "Prostate cancer (PCa) is the most frequently diagnosed non-skin tumor in the western world in men. The lifetime risk of an American man to develop a clinically significant PCa is between 17 and 20% dependent on ethnic origin. In the western world, mortality from PCa varies between 2.82 and 4.73%. PCa is responsible for 12.7% of total cancer death in American men and is the second leading cause of cancer death after lung cancer [1]. The incidence of PCa is increasing with age. The probability of being diagnosed with prostate cancer is 1 in 19,299 for men younger than 40 years, 1 in 45 for men aged 40 through 59 years, and 1 in 7 for men aged 60 through 79 years [2]. Although there are considerable geographical differences in lifetime risk for clinically significant PCa, there seems to be an equal spread for microfocal PCa [3]. In view of the increased life expectancy, the absolute number of clinically significant PCa’s will probably increase in the coming decades. In this way, to prevent an equal rise in mortality, early detection of PCa will become essential, as will the detection of premalignant lesions such as Prostatic Intraepithelial Neoplasia (PIN)." @default.
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- W2023408367 date "2005-09-01" @default.
- W2023408367 modified "2023-10-16" @default.
- W2023408367 title "Prostatic Intraepithelial Neoplasia (PIN): Importance and Clinical Management" @default.
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- W2023408367 doi "https://doi.org/10.1016/j.eururo.2005.03.015" @default.
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