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• W2023410141 abstract "Titanium oxide films were deposited onto low temperature isotropic carbon (LTI-carbon), a prevailing material used for mechanical heart valve fabrication, by ion beam enhanced deposition (IBED). The composition and structure of the film were studied by glancing angle X-ray diffraction (GAXRD) and Auger electron analysis (AES). The results show that the film is dominated by polycrystalline Ti2O3, as well as TiO2. The elements are well distributed along the depth profile. The surface morphologies of LTI-carbon and titanium oxide film are very similar when observed by atomic force microscopy (AFM), which indicated that the surface morphology has no significant influence on the protein adsorption properties of the samples. The protein adsorption behavior was investigated in a HSA/HFG binary system by means of 125I labeling. The results show that both proteins adsorbed preferentially on LTI-carbon rather than on titanium oxide film. In the HSA/HFG binary system, the adsorption behavior of one protein is inhibited as the concentration of the other protein increases. When the concentrations of both proteins were kept constant, the amount of adsorbed HSA strongly increased with time on titanium oxide, but less so on LTI-carbon. However, the adsorption of HFG showed the opposite behavior. It is concluded that titanium oxide film exhibits a HSA-preferred adsorption property, whereas LTI-carbon shows no preferential adsorption. This is mainly attributed to the different surface energy of LTI-carbon and titanium oxide film." @default.
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• W2023410141 date "2003-07-01" @default.
• W2023410141 modified "2023-10-15" @default.
• W2023410141 title "Competitive adsorption behavior of human serum albumin and fibrinogen on titanium oxide films coated on LTI-carbon by IBED" @default.
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• W2023410141 doi "https://doi.org/10.1016/s0927-7765(03)00078-x" @default.
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