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- W2023422641 abstract "Abstract Objectives. The objectives of the present study were (1) to evaluate the presser response to an isometric handgrip exercise in normotensive black and white males; (2) to measure plasma catecholamine levels pre‐ and post‐exercise, as an index of sympathetic nervous system activity; and (3) to quantify the pressor response to bolus intravenous injections of phenylephrine (an α‐specific agonist). Methods. Cardiovascular and catecholamine responses to an isometric handgrip exercise (3 minutes at 30% MVC) were measured in 15 normotensive blacks and whites. In another phase of the study, pressor responses to bolus injections of phenylephrine were assessed to evaluate α‐adrenergic sensitivity. Results. The blood pressure in the blacks increased from 119/69 to 160/120 mm HG during isometric exercise, while in the whites it increased from 118/67 to 153/110 mm HG. The blacks exhibited a greater diastolic blood pressure reactivity, as evidenced by a significant race × time interaction (p < 0.05). The heart rate responses were not significantly different between the two groups. The plasma levels of norepinephrine were similar at rest, but were 25% lower in the blacks than in the whites following isometric exercise (p < 0.01). Black subjects also demonstrated an increased pressor response to intravenous injections of phenylephrine at rest (p<0.05). Conclusions. The enhanced vascular sensitivity to norepinephrine may have contributed to the greater exercise pressor response in the blacks." @default.
- W2023422641 created "2016-06-24" @default.
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- W2023422641 date "1997-03-01" @default.
- W2023422641 modified "2023-09-26" @default.
- W2023422641 title "Cardiovascular and plasma catecholamine response to static exercise in normotensive blacks and whites" @default.
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- W2023422641 doi "https://doi.org/10.1080/13557858.1997.9961821" @default.
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