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- W2023429152 abstract "The accumulation of 35S in various tissues of male and female albino rats fed [35S]sulphate or [35S]sulphite in daily doses equivalent to 50 mg SO2/kg for 2, 7 and 14 days was compared. The accumulation appeared similar for all the tissues studied except skin and hair, stomach and possibly the intestine, in which a relatively greater accumulation of 35S was demonstrated when sulphite was fed. When [35S]sulphited rat-serum protein (134–169 mg) was fed to rats by stomach tube, absorption and utilization of the protein was indicated by excretion of 40–55% of the label in the urine within 24 hr, 90% of this excreted radioactivity being in the form of sulphate. Radioactivity from this same sulphited protein (56 mg) injected into the jugular vein was retained within the body to a much greater extent (48%) than ingested protein label (7–17%) at 24 hr. The marked difference in the distribution of 35S from sulphited rat-serum protein injected into the blood stream from that found with ingested free [35S]sulphite suggests that sulphited plasma proteins may not be intermediates in the metabolism of ingested sulphite. Rats fed diets containing autoclaved, metabisulphite-treated casein for 7 wk grew as well as control animals fed diets containing autoclaved unsulphited casein." @default.
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- W2023429152 date "1974-10-01" @default.
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- W2023429152 title "Accumulation of ingested sulphite- and sulphate-sulphur and utilization of sulphited proteins by rats" @default.
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- W2023429152 doi "https://doi.org/10.1016/0015-6264(74)90234-x" @default.
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