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• W2023441786 abstract "Abstract The occurrence of malignant neoplasia in lower animals is considered, and it is concluded that tumours occur not only in all vertebrate classes but also in some invertebrates. Thus, malignant cell populations can develop in animals which do not have cellular defence mechanisms involving immunoglobulins. The significance of natural cytotoxicity is discussed, and it is concluded that natural killer cells may not only provide a link between the natural and immunological cellular defence mechanisms during the lives of individual vertebrate animals, but may also offer some indication of how vertebrate cell-mediated immunity may have evolved from pre-existing natural cellular defence mechanisms." @default.
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• W2023441786 date "1981-01-01" @default.
• W2023441786 modified "2023-09-24" @default.
• W2023441786 title "The phylogeny of tumour immunity" @default.
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• W2023441786 doi "https://doi.org/10.1016/0145-305x(81)90006-9" @default.
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