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• W2023447188 startingPage "36" @default.
• W2023447188 abstract "In order to assess the usefulness of A549, L-2, and AK-D cell lines as model systems for alveolar type II cells, we compared their phospholipid composition to that of fibroblasts grown under similar conditions. The percentage of disaturated phosphatidylcholine and phosphatidylglycerol, key phospholipids of purified surface-active material, was the same in epithelial cells and fibroblasts. When A549 cells were maintained in serum-free media for two days, ultrastructural examination showed an increase in cytoplasmic lamellar inclusions but there was no change in the percentage of disaturated phosphatidylcholine or phosphatidylglycerol. Because the lipid content of these cultured cells was very different from that of freshly isolated rat type II cells, we conclude that their suitability as model cell systems for type II cells is questionable." @default.
• W2023447188 created "2016-06-24" @default.
• W2023447188 creator A5009526225 @default.
• W2023447188 creator A5066268217 @default.
• W2023447188 date "1980-01-01" @default.
• W2023447188 modified "2023-10-17" @default.
• W2023447188 title "Phospholipid composition and ultrastructure of A549 cells and other cultured pulmonary epithelial cells of presumed type II cell origin" @default.
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• W2023447188 doi "https://doi.org/10.1016/0005-2760(80)90222-2" @default.
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