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• W2023447778 abstract "We have developed an episomal replicating expression vector in which the SV40 gene coding for the large T-antigen was replaced by chromosomal scaffold/matrix attached regions. Southern analysis as well as vector rescue experiments in CHO cells and in Escherichia coli demonstrate that the vector replicates episomally in CHO cells. It occurs in a very low copy number in the cells and is stably maintained over more than 100 generations without selection pressure." @default.
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• W2023447778 date "1999-01-01" @default.
• W2023447778 modified "2023-10-15" @default.
• W2023447778 title "A vector based on the SV40 origin of replication and chromosomal S/MARs replicates episomally in CHO cells" @default.
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• W2023447778 doi "https://doi.org/10.1093/nar/27.2.426" @default.
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