Matches in SemOpenAlex for { <https://semopenalex.org/work/W2023449786> ?p ?o ?g. }
Showing items 1 to 88 of
88
with 100 items per page.
- W2023449786 endingPage "232" @default.
- W2023449786 startingPage "229" @default.
- W2023449786 abstract "Deletion mapping of a medulloblastoma tumor panel revealed loss of distal chromosome 17p13.3 sequences in tumors from 14 of 32 patients (44%). Of the 14 tumors showing loss of heterozygosity by restriction fragment length polymorphism analysis, 14 of 14 (100%) displayed loss of the telomeric marker p144-D6 (D17S34), while a probe for the ABR gene on 17p13.3 was lost in 7 of 8 (88%) informative cases. Using pulsed-field gel electrophoresis, we localized the polymorphic marker (VNTR-A) of the ABR gene locus to within 220 kb of the p144-D6 locus. A cosmid contig constructed in this region was used to demonstrate by fluorescence in situ hybridization that the ABR gene is oriented transcriptionally 5' to 3' toward the telomere. This report provides new physical mapping data for the ABR gene, which has not been previously shown to be deleted in medulloblastoma. These results provide further evidence for the existence of a second tumor suppressor gene distinct from p53 on distal chromosome 17p." @default.
- W2023449786 created "2016-06-24" @default.
- W2023449786 creator A5014034343 @default.
- W2023449786 creator A5030361711 @default.
- W2023449786 creator A5048828173 @default.
- W2023449786 creator A5059576705 @default.
- W2023449786 creator A5081804855 @default.
- W2023449786 creator A5082830075 @default.
- W2023449786 date "1994-09-01" @default.
- W2023449786 modified "2023-10-14" @default.
- W2023449786 title "Physical Mapping of Chromosome 17p13.3 in the Region of a Putative Tumor Suppressor Gene Important in Medulloblastoma" @default.
- W2023449786 doi "https://doi.org/10.1006/geno.1994.1481" @default.
- W2023449786 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/7829075" @default.
- W2023449786 hasPublicationYear "1994" @default.
- W2023449786 type Work @default.
- W2023449786 sameAs 2023449786 @default.
- W2023449786 citedByCount "88" @default.
- W2023449786 countsByYear W20234497862013 @default.
- W2023449786 countsByYear W20234497862014 @default.
- W2023449786 countsByYear W20234497862015 @default.
- W2023449786 countsByYear W20234497862016 @default.
- W2023449786 countsByYear W20234497862017 @default.
- W2023449786 countsByYear W20234497862018 @default.
- W2023449786 countsByYear W20234497862019 @default.
- W2023449786 countsByYear W20234497862020 @default.
- W2023449786 countsByYear W20234497862021 @default.
- W2023449786 countsByYear W20234497862022 @default.
- W2023449786 crossrefType "journal-article" @default.
- W2023449786 hasAuthorship W2023449786A5014034343 @default.
- W2023449786 hasAuthorship W2023449786A5030361711 @default.
- W2023449786 hasAuthorship W2023449786A5048828173 @default.
- W2023449786 hasAuthorship W2023449786A5059576705 @default.
- W2023449786 hasAuthorship W2023449786A5081804855 @default.
- W2023449786 hasAuthorship W2023449786A5082830075 @default.
- W2023449786 hasConcept C104317684 @default.
- W2023449786 hasConcept C122735190 @default.
- W2023449786 hasConcept C141231307 @default.
- W2023449786 hasConcept C143589142 @default.
- W2023449786 hasConcept C153911025 @default.
- W2023449786 hasConcept C167752854 @default.
- W2023449786 hasConcept C180754005 @default.
- W2023449786 hasConcept C2777542201 @default.
- W2023449786 hasConcept C2778264664 @default.
- W2023449786 hasConcept C30481170 @default.
- W2023449786 hasConcept C35101798 @default.
- W2023449786 hasConcept C54355233 @default.
- W2023449786 hasConcept C555283112 @default.
- W2023449786 hasConcept C59582021 @default.
- W2023449786 hasConcept C84597430 @default.
- W2023449786 hasConcept C86803240 @default.
- W2023449786 hasConceptScore W2023449786C104317684 @default.
- W2023449786 hasConceptScore W2023449786C122735190 @default.
- W2023449786 hasConceptScore W2023449786C141231307 @default.
- W2023449786 hasConceptScore W2023449786C143589142 @default.
- W2023449786 hasConceptScore W2023449786C153911025 @default.
- W2023449786 hasConceptScore W2023449786C167752854 @default.
- W2023449786 hasConceptScore W2023449786C180754005 @default.
- W2023449786 hasConceptScore W2023449786C2777542201 @default.
- W2023449786 hasConceptScore W2023449786C2778264664 @default.
- W2023449786 hasConceptScore W2023449786C30481170 @default.
- W2023449786 hasConceptScore W2023449786C35101798 @default.
- W2023449786 hasConceptScore W2023449786C54355233 @default.
- W2023449786 hasConceptScore W2023449786C555283112 @default.
- W2023449786 hasConceptScore W2023449786C59582021 @default.
- W2023449786 hasConceptScore W2023449786C84597430 @default.
- W2023449786 hasConceptScore W2023449786C86803240 @default.
- W2023449786 hasIssue "1" @default.
- W2023449786 hasLocation W20234497861 @default.
- W2023449786 hasLocation W20234497862 @default.
- W2023449786 hasOpenAccess W2023449786 @default.
- W2023449786 hasPrimaryLocation W20234497861 @default.
- W2023449786 hasRelatedWork W185768814 @default.
- W2023449786 hasRelatedWork W1978342775 @default.
- W2023449786 hasRelatedWork W2008510086 @default.
- W2023449786 hasRelatedWork W2010863322 @default.
- W2023449786 hasRelatedWork W2014773957 @default.
- W2023449786 hasRelatedWork W2023449786 @default.
- W2023449786 hasRelatedWork W2036247923 @default.
- W2023449786 hasRelatedWork W2071628850 @default.
- W2023449786 hasRelatedWork W2144816373 @default.
- W2023449786 hasRelatedWork W3092862316 @default.
- W2023449786 hasVolume "23" @default.
- W2023449786 isParatext "false" @default.
- W2023449786 isRetracted "false" @default.
- W2023449786 magId "2023449786" @default.
- W2023449786 workType "article" @default.