FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2023450423> ?p ?o ?g. }

• W2023450423 endingPage "7713" @default.
• W2023450423 startingPage "7709" @default.
• W2023450423 abstract "Low concentrations (0.5-1 microM) of cytochalasins inhibit the thrombin-stimulated polymerization of monomeric actin to filamentous actin in platelets. Similar concentrations of cytochalasin B inhibit the formation and metabolism of arachidonic acid in horse platelets stimulated by low concentrations of thrombin (0.1-0.5 unit/ml). However, the release of serotonin is not inhibited by cytochalasin B. Cytochalasins B and D (0.5-1 microM) markedly reduce, in thrombin-stimulated human or horse platelets, the metabolism of the liberated arachidonic acid by cyclooxygenase activity to thromboxane B2 and 12-hydroxy-5,8,10-heptadecatrienoic acid and the conversion of arachidonic acid by lipoxygenase activity to 12-hydroxy-5,8,10,14-icosatetraenoic acid. The generation of arachidonic acid from platelet phospholipids and the formation of phosphatidic acid are much less affected by cytochalasin B or D. Cytochalasins do not directly inhibit platelet cyclooxygenase, lipoxygenase, phospholipase A2, or phosphatidyl-inositol-specific phospholipase C. In addition, the metabolism of exogenously added arachidonic acid by intact platelets is not inhibited by cytochalasins B and D. The results indicate that polymerization of actin in platelets stimulated by thrombin may be required for the effective metabolism of arachidonic acid released from platelet phospholipids." @default.
• W2023450423 created "2016-06-24" @default.
• W2023450423 creator A5015728629 @default.
• W2023450423 creator A5068145395 @default.
• W2023450423 creator A5090804771 @default.
• W2023450423 date "1982-12-01" @default.
• W2023450423 modified "2023-10-14" @default.
• W2023450423 title "Cytochalasins inhibit arachidonic acid metabolism in thrombin-stimulated platelets." @default.
• W2023450423 cites W1483045044 @default.
• W2023450423 cites W1533165549 @default.
• W2023450423 cites W1555808871 @default.
• W2023450423 cites W1558484374 @default.
• W2023450423 cites W1564176844 @default.
• W2023450423 cites W1598223054 @default.
• W2023450423 cites W1841826782 @default.
• W2023450423 cites W1970038583 @default.
• W2023450423 cites W1972719296 @default.
• W2023450423 cites W1979976729 @default.
• W2023450423 cites W1980966579 @default.
• W2023450423 cites W1983914474 @default.
• W2023450423 cites W2001678988 @default.
• W2023450423 cites W2008251723 @default.
• W2023450423 cites W2018289835 @default.
• W2023450423 cites W2020240409 @default.
• W2023450423 cites W2021991370 @default.
• W2023450423 cites W2026079918 @default.
• W2023450423 cites W2034005338 @default.
• W2023450423 cites W2039723960 @default.
• W2023450423 cites W2045141737 @default.
• W2023450423 cites W2056939715 @default.
• W2023450423 cites W2070206012 @default.
• W2023450423 cites W2072901474 @default.
• W2023450423 cites W2086441678 @default.
• W2023450423 cites W2100837269 @default.
• W2023450423 cites W2166241889 @default.
• W2023450423 cites W2415615563 @default.
• W2023450423 cites W2462572590 @default.
• W2023450423 cites W2464591870 @default.
• W2023450423 cites W2416502054 @default.
• W2023450423 doi "https://doi.org/10.1073/pnas.79.24.7709" @default.
• W2023450423 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/347417" @default.
• W2023450423 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/6961445" @default.
• W2023450423 hasPublicationYear "1982" @default.
• W2023450423 type Work @default.
• W2023450423 sameAs 2023450423 @default.
• W2023450423 citedByCount "23" @default.
• W2023450423 countsByYear W20234504232017 @default.
• W2023450423 crossrefType "journal-article" @default.
• W2023450423 hasAuthorship W2023450423A5015728629 @default.
• W2023450423 hasAuthorship W2023450423A5068145395 @default.
• W2023450423 hasAuthorship W2023450423A5090804771 @default.
• W2023450423 hasBestOaLocation W20234504232 @default.
• W2023450423 hasConcept C142669718 @default.
• W2023450423 hasConcept C1491633281 @default.
• W2023450423 hasConcept C181199279 @default.
• W2023450423 hasConcept C185592680 @default.
• W2023450423 hasConcept C203014093 @default.
• W2023450423 hasConcept C2775995422 @default.
• W2023450423 hasConcept C2776551241 @default.
• W2023450423 hasConcept C2776909261 @default.
• W2023450423 hasConcept C2777292125 @default.
• W2023450423 hasConcept C2778078955 @default.
• W2023450423 hasConcept C2778918659 @default.
• W2023450423 hasConcept C2779012151 @default.
• W2023450423 hasConcept C2780857362 @default.
• W2023450423 hasConcept C41625074 @default.
• W2023450423 hasConcept C55493867 @default.
• W2023450423 hasConcept C62231903 @default.
• W2023450423 hasConcept C86803240 @default.
• W2023450423 hasConcept C89560881 @default.
• W2023450423 hasConceptScore W2023450423C142669718 @default.
• W2023450423 hasConceptScore W2023450423C1491633281 @default.
• W2023450423 hasConceptScore W2023450423C181199279 @default.
• W2023450423 hasConceptScore W2023450423C185592680 @default.
• W2023450423 hasConceptScore W2023450423C203014093 @default.
• W2023450423 hasConceptScore W2023450423C2775995422 @default.
• W2023450423 hasConceptScore W2023450423C2776551241 @default.
• W2023450423 hasConceptScore W2023450423C2776909261 @default.
• W2023450423 hasConceptScore W2023450423C2777292125 @default.
• W2023450423 hasConceptScore W2023450423C2778078955 @default.
• W2023450423 hasConceptScore W2023450423C2778918659 @default.
• W2023450423 hasConceptScore W2023450423C2779012151 @default.
• W2023450423 hasConceptScore W2023450423C2780857362 @default.
• W2023450423 hasConceptScore W2023450423C41625074 @default.
• W2023450423 hasConceptScore W2023450423C55493867 @default.
• W2023450423 hasConceptScore W2023450423C62231903 @default.
• W2023450423 hasConceptScore W2023450423C86803240 @default.
• W2023450423 hasConceptScore W2023450423C89560881 @default.
• W2023450423 hasIssue "24" @default.
• W2023450423 hasLocation W20234504231 @default.
• W2023450423 hasLocation W20234504232 @default.
• W2023450423 hasLocation W20234504233 @default.
• W2023450423 hasOpenAccess W2023450423 @default.
• W2023450423 hasPrimaryLocation W20234504231 @default.
• W2023450423 hasRelatedWork W1006316367 @default.
• W2023450423 hasRelatedWork W1539889565 @default.
• W2023450423 hasRelatedWork W1555704933 @default.
• W2023450423 hasRelatedWork W1965290216 @default.

• next