FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2023459166> ?p ?o ?g. }

• W2023459166 endingPage "227" @default.
• W2023459166 startingPage "227" @default.
• W2023459166 abstract "Protein cages are promising nanoplatform candidates for efficient delivery systems due to their homogenous size and structure with high biocompatibility and biodegradability. In this study, we investigate the potential of lumazine synthase protein cage as an antigen delivery system to dendritic cells (DCs), which induce antigen-specific T cell proliferation.Ovalbumin (OVA) peptides OT-1 (SIINFEKL) and OT-2 (ISQAVHAAHAEINEAGR) were genetically inserted to lumazine synthase and each protein cage was over-expressed in Escherichia coli as a soluble protein. The efficiency of antigen delivery and the resulting antigen-specific T cell proliferation by DCs was examined in vitro as well as in vivo.We successfully generated and characterized OVA peptides carrying lumazine synthase protein cages. The OT-1 and OT-2 peptides carried by lumazine synthases were efficiently delivered and processed by DCs in vitro as well as in vivo, and induced proliferation of OT-1-specific CD8(+)T cells and OT-2-specific CD4(+)T cells.Our data demonstrate the potential of lumazine synthase protein cage being used as a novel antigen delivery system for DC-based vaccine development in future clinical applications." @default.
• W2023459166 created "2016-06-24" @default.
• W2023459166 creator A5002625774 @default.
• W2023459166 creator A5022120708 @default.
• W2023459166 creator A5023309255 @default.
• W2023459166 creator A5041027236 @default.
• W2023459166 date "2014-01-01" @default.
• W2023459166 modified "2023-09-25" @default.
• W2023459166 title "Lumazine synthase protein cage nanoparticles as antigen delivery nanoplatforms for dendritic cell-based vaccine development" @default.
• W2023459166 cites W1732892700 @default.
• W2023459166 cites W1979882122 @default.
• W2023459166 cites W2012425332 @default.
• W2023459166 cites W2027321263 @default.
• W2023459166 cites W2045032030 @default.
• W2023459166 cites W2048492655 @default.
• W2023459166 cites W2062254683 @default.
• W2023459166 cites W2063840206 @default.
• W2023459166 cites W2083146987 @default.
• W2023459166 cites W2083249659 @default.
• W2023459166 cites W2096139318 @default.
• W2023459166 cites W2105951661 @default.
• W2023459166 cites W2111975769 @default.
• W2023459166 cites W2115856953 @default.
• W2023459166 cites W2125576205 @default.
• W2023459166 cites W2164276960 @default.
• W2023459166 cites W2169958419 @default.
• W2023459166 cites W2171919355 @default.
• W2023459166 cites W2317947423 @default.
• W2023459166 cites W2333852915 @default.
• W2023459166 cites W2335364655 @default.
• W2023459166 doi "https://doi.org/10.7774/cevr.2014.3.2.227" @default.
• W2023459166 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4083076" @default.
• W2023459166 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/25003097" @default.
• W2023459166 hasPublicationYear "2014" @default.
• W2023459166 type Work @default.
• W2023459166 sameAs 2023459166 @default.
• W2023459166 citedByCount "42" @default.
• W2023459166 countsByYear W20234591662014 @default.
• W2023459166 countsByYear W20234591662015 @default.
• W2023459166 countsByYear W20234591662016 @default.
• W2023459166 countsByYear W20234591662017 @default.
• W2023459166 countsByYear W20234591662018 @default.
• W2023459166 countsByYear W20234591662019 @default.
• W2023459166 countsByYear W20234591662020 @default.
• W2023459166 countsByYear W20234591662021 @default.
• W2023459166 countsByYear W20234591662022 @default.
• W2023459166 countsByYear W20234591662023 @default.
• W2023459166 crossrefType "journal-article" @default.
• W2023459166 hasAuthorship W2023459166A5002625774 @default.
• W2023459166 hasAuthorship W2023459166A5022120708 @default.
• W2023459166 hasAuthorship W2023459166A5023309255 @default.
• W2023459166 hasAuthorship W2023459166A5041027236 @default.
• W2023459166 hasBestOaLocation W20234591661 @default.
• W2023459166 hasConcept C147483822 @default.
• W2023459166 hasConcept C150903083 @default.
• W2023459166 hasConcept C154317977 @default.
• W2023459166 hasConcept C185592680 @default.
• W2023459166 hasConcept C202751555 @default.
• W2023459166 hasConcept C203014093 @default.
• W2023459166 hasConcept C207001950 @default.
• W2023459166 hasConcept C2776946954 @default.
• W2023459166 hasConcept C2778170410 @default.
• W2023459166 hasConcept C55493867 @default.
• W2023459166 hasConcept C67662055 @default.
• W2023459166 hasConcept C86803240 @default.
• W2023459166 hasConcept C95444343 @default.
• W2023459166 hasConceptScore W2023459166C147483822 @default.
• W2023459166 hasConceptScore W2023459166C150903083 @default.
• W2023459166 hasConceptScore W2023459166C154317977 @default.
• W2023459166 hasConceptScore W2023459166C185592680 @default.
• W2023459166 hasConceptScore W2023459166C202751555 @default.
• W2023459166 hasConceptScore W2023459166C203014093 @default.
• W2023459166 hasConceptScore W2023459166C207001950 @default.
• W2023459166 hasConceptScore W2023459166C2776946954 @default.
• W2023459166 hasConceptScore W2023459166C2778170410 @default.
• W2023459166 hasConceptScore W2023459166C55493867 @default.
• W2023459166 hasConceptScore W2023459166C67662055 @default.
• W2023459166 hasConceptScore W2023459166C86803240 @default.
• W2023459166 hasConceptScore W2023459166C95444343 @default.
• W2023459166 hasIssue "2" @default.
• W2023459166 hasLocation W20234591661 @default.
• W2023459166 hasLocation W20234591662 @default.
• W2023459166 hasLocation W20234591663 @default.
• W2023459166 hasLocation W20234591664 @default.
• W2023459166 hasLocation W20234591665 @default.
• W2023459166 hasOpenAccess W2023459166 @default.
• W2023459166 hasPrimaryLocation W20234591661 @default.
• W2023459166 hasRelatedWork W1967074775 @default.
• W2023459166 hasRelatedWork W1997402777 @default.
• W2023459166 hasRelatedWork W2034408472 @default.
• W2023459166 hasRelatedWork W2039706531 @default.
• W2023459166 hasRelatedWork W2078221811 @default.
• W2023459166 hasRelatedWork W2092202838 @default.
• W2023459166 hasRelatedWork W2096747204 @default.
• W2023459166 hasRelatedWork W2106934028 @default.
• W2023459166 hasRelatedWork W2746448424 @default.
• W2023459166 hasRelatedWork W2515434147 @default.
• W2023459166 hasVolume "3" @default.

• next