Matches in SemOpenAlex for { <https://semopenalex.org/work/W2023467037> ?p ?o ?g. }
- W2023467037 endingPage "1041" @default.
- W2023467037 startingPage "1032" @default.
- W2023467037 abstract "To assess the potential of using the residual phosphorylation of histone H2AX (gammaH2AX) after irradiation as a marker of radiosensitivity in vitro.Confluent cell cultures of FaDu and SKX human squamous cell carcinoma lines were irradiated with graded single doses. Twenty-four hours after irradiation cells were seeded for standard colony forming assay (CFA). In parallel, staining for gammaH2AX was performed to visualise the residual foci.In the CFA, FaDu showed a higher radioresistance than SKX. After analysis of the residual foci data, we constructed 'predicted' survival curves using two different methods. First, the proportion of nuclei with <3 foci was found to correlate closely with the observed surviving fraction (SF) in FaDu, with a slight overestimation of the true SF in SKX. Second, there was a strong linear correlation of the mean number of residual foci and observed -lnSF. Based on regression analysis, we calculated the SF for both cell lines based on the mean number of residual gammaH2AX foci. This second approach again led to a good correlation of predicted and observed SF values in FaDu and a (slight) overestimation in SKX.In the two cell lines investigated the mean number of residual foci of gammaH2AX can be used to predict differences in the radiation dose response relationship in vitro." @default.
- W2023467037 created "2016-06-24" @default.
- W2023467037 creator A5003759958 @default.
- W2023467037 creator A5028492548 @default.
- W2023467037 creator A5030310687 @default.
- W2023467037 creator A5037651119 @default.
- W2023467037 creator A5044442214 @default.
- W2023467037 creator A5066111006 @default.
- W2023467037 creator A5070431570 @default.
- W2023467037 creator A5083101824 @default.
- W2023467037 date "2009-11-01" @default.
- W2023467037 modified "2023-09-26" @default.
- W2023467037 title "Prediction of clonogenic cell survival curves based on the number of residual DNA double strand breaks measured by γH2AX staining" @default.
- W2023467037 cites W1564224574 @default.
- W2023467037 cites W1978331091 @default.
- W2023467037 cites W1980017984 @default.
- W2023467037 cites W1985775217 @default.
- W2023467037 cites W1988497624 @default.
- W2023467037 cites W1998129814 @default.
- W2023467037 cites W1999796994 @default.
- W2023467037 cites W2012126331 @default.
- W2023467037 cites W2014062314 @default.
- W2023467037 cites W2014928083 @default.
- W2023467037 cites W2015925058 @default.
- W2023467037 cites W2016434246 @default.
- W2023467037 cites W2019405732 @default.
- W2023467037 cites W2026261342 @default.
- W2023467037 cites W2027630134 @default.
- W2023467037 cites W2030266950 @default.
- W2023467037 cites W2032980832 @default.
- W2023467037 cites W2033172828 @default.
- W2023467037 cites W2046165135 @default.
- W2023467037 cites W2051193631 @default.
- W2023467037 cites W2052040839 @default.
- W2023467037 cites W2060371289 @default.
- W2023467037 cites W2067328670 @default.
- W2023467037 cites W2075175820 @default.
- W2023467037 cites W2077709632 @default.
- W2023467037 cites W2081702399 @default.
- W2023467037 cites W2089519759 @default.
- W2023467037 cites W2096136751 @default.
- W2023467037 cites W2097477376 @default.
- W2023467037 cites W2099627146 @default.
- W2023467037 cites W2102560312 @default.
- W2023467037 cites W2106845421 @default.
- W2023467037 cites W2114616141 @default.
- W2023467037 cites W2130883309 @default.
- W2023467037 cites W2133853290 @default.
- W2023467037 cites W2143493476 @default.
- W2023467037 cites W2151411596 @default.
- W2023467037 cites W2152745581 @default.
- W2023467037 cites W2158805945 @default.
- W2023467037 cites W2160407692 @default.
- W2023467037 doi "https://doi.org/10.3109/09553000903242149" @default.
- W2023467037 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/19895280" @default.
- W2023467037 hasPublicationYear "2009" @default.
- W2023467037 type Work @default.
- W2023467037 sameAs 2023467037 @default.
- W2023467037 citedByCount "71" @default.
- W2023467037 countsByYear W20234670372012 @default.
- W2023467037 countsByYear W20234670372013 @default.
- W2023467037 countsByYear W20234670372014 @default.
- W2023467037 countsByYear W20234670372015 @default.
- W2023467037 countsByYear W20234670372016 @default.
- W2023467037 countsByYear W20234670372017 @default.
- W2023467037 countsByYear W20234670372018 @default.
- W2023467037 countsByYear W20234670372019 @default.
- W2023467037 countsByYear W20234670372021 @default.
- W2023467037 countsByYear W20234670372022 @default.
- W2023467037 countsByYear W20234670372023 @default.
- W2023467037 crossrefType "journal-article" @default.
- W2023467037 hasAuthorship W2023467037A5003759958 @default.
- W2023467037 hasAuthorship W2023467037A5028492548 @default.
- W2023467037 hasAuthorship W2023467037A5030310687 @default.
- W2023467037 hasAuthorship W2023467037A5037651119 @default.
- W2023467037 hasAuthorship W2023467037A5044442214 @default.
- W2023467037 hasAuthorship W2023467037A5066111006 @default.
- W2023467037 hasAuthorship W2023467037A5070431570 @default.
- W2023467037 hasAuthorship W2023467037A5083101824 @default.
- W2023467037 hasConcept C11413529 @default.
- W2023467037 hasConcept C117262875 @default.
- W2023467037 hasConcept C126322002 @default.
- W2023467037 hasConcept C153911025 @default.
- W2023467037 hasConcept C155512373 @default.
- W2023467037 hasConcept C185592680 @default.
- W2023467037 hasConcept C202751555 @default.
- W2023467037 hasConcept C206684579 @default.
- W2023467037 hasConcept C41008148 @default.
- W2023467037 hasConcept C509974204 @default.
- W2023467037 hasConcept C54355233 @default.
- W2023467037 hasConcept C58962609 @default.
- W2023467037 hasConcept C71924100 @default.
- W2023467037 hasConcept C74864618 @default.
- W2023467037 hasConcept C81885089 @default.
- W2023467037 hasConcept C86803240 @default.
- W2023467037 hasConceptScore W2023467037C11413529 @default.
- W2023467037 hasConceptScore W2023467037C117262875 @default.
- W2023467037 hasConceptScore W2023467037C126322002 @default.