FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2023474682> ?p ?o ?g. }

• W2023474682 endingPage "e1382" @default.
• W2023474682 startingPage "e1382" @default.
• W2023474682 abstract "Background The vast majority of genetic risk factors for complex diseases have, taken individually, a small effect on the end phenotype. Population-based association studies therefore need very large sample sizes to detect significant differences between affected and non-affected individuals. Including thousands of affected individuals in a study requires recruitment in numerous centers, possibly from different geographic regions. Unfortunately such a recruitment strategy is likely to complicate the study design and to generate concerns regarding population stratification. Methodology/Principal Findings We analyzed 9,751 individuals representing three main ethnic groups - Europeans, Arabs and South Asians - that had been enrolled from 154 centers involving 52 countries for a global case/control study of acute myocardial infarction. All individuals were genotyped at 103 candidate genes using 1,536 SNPs selected with a tagging strategy that captures most of the genetic diversity in different populations. We show that relying solely on self-reported ethnicity is not sufficient to exclude population stratification and we present additional methods to identify and correct for stratification. Conclusions/Significance Our results highlight the importance of carefully addressing population stratification and of carefully “cleaning” the sample prior to analyses to obtain stronger signals of association and to avoid spurious results." @default.
• W2023474682 created "2016-06-24" @default.
• W2023474682 creator A5018419311 @default.
• W2023474682 creator A5035095307 @default.
• W2023474682 creator A5038574644 @default.
• W2023474682 creator A5054423486 @default.
• W2023474682 creator A5058205892 @default.
• W2023474682 creator A5060105528 @default.
• W2023474682 creator A5075729521 @default.
• W2023474682 creator A5080707052 @default.
• W2023474682 date "2008-01-02" @default.
• W2023474682 modified "2023-10-12" @default.
• W2023474682 title "Correction of Population Stratification in Large Multi-Ethnic Association Studies" @default.
• W2023474682 cites W1969790498 @default.
• W2023474682 cites W1986265706 @default.
• W2023474682 cites W1998234914 @default.
• W2023474682 cites W2002395285 @default.
• W2023474682 cites W2008047653 @default.
• W2023474682 cites W2009144436 @default.
• W2023474682 cites W2015408724 @default.
• W2023474682 cites W2020807418 @default.
• W2023474682 cites W2020937422 @default.
• W2023474682 cites W2023289636 @default.
• W2023474682 cites W2025143098 @default.
• W2023474682 cites W2028818536 @default.
• W2023474682 cites W2044664066 @default.
• W2023474682 cites W2047923046 @default.
• W2023474682 cites W2050767863 @default.
• W2023474682 cites W2056748059 @default.
• W2023474682 cites W2064310756 @default.
• W2023474682 cites W2067097191 @default.
• W2023474682 cites W2068525568 @default.
• W2023474682 cites W2069325628 @default.
• W2023474682 cites W2071199144 @default.
• W2023474682 cites W2097576041 @default.
• W2023474682 cites W2098126593 @default.
• W2023474682 cites W2098980155 @default.
• W2023474682 cites W2104738846 @default.
• W2023474682 cites W2106002960 @default.
• W2023474682 cites W2108169091 @default.
• W2023474682 cites W2109716699 @default.
• W2023474682 cites W2120483845 @default.
• W2023474682 cites W2121101037 @default.
• W2023474682 cites W2123184366 @default.
• W2023474682 cites W2123466824 @default.
• W2023474682 cites W2126639509 @default.
• W2023474682 cites W2139411388 @default.
• W2023474682 cites W2150542380 @default.
• W2023474682 cites W2155121555 @default.
• W2023474682 cites W2156732616 @default.
• W2023474682 cites W2156918287 @default.
• W2023474682 cites W2168300089 @default.
• W2023474682 cites W2217809488 @default.
• W2023474682 cites W2620406790 @default.
• W2023474682 cites W45915410 @default.
• W2023474682 cites W70104078 @default.
• W2023474682 doi "https://doi.org/10.1371/journal.pone.0001382" @default.
• W2023474682 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/2198793" @default.
• W2023474682 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/18196181" @default.
• W2023474682 hasPublicationYear "2008" @default.
• W2023474682 type Work @default.
• W2023474682 sameAs 2023474682 @default.
• W2023474682 citedByCount "59" @default.
• W2023474682 countsByYear W20234746822012 @default.
• W2023474682 countsByYear W20234746822013 @default.
• W2023474682 countsByYear W20234746822014 @default.
• W2023474682 countsByYear W20234746822015 @default.
• W2023474682 countsByYear W20234746822016 @default.
• W2023474682 countsByYear W20234746822017 @default.
• W2023474682 countsByYear W20234746822018 @default.
• W2023474682 countsByYear W20234746822019 @default.
• W2023474682 countsByYear W20234746822020 @default.
• W2023474682 countsByYear W20234746822021 @default.
• W2023474682 countsByYear W20234746822022 @default.
• W2023474682 countsByYear W20234746822023 @default.
• W2023474682 crossrefType "journal-article" @default.
• W2023474682 hasAuthorship W2023474682A5018419311 @default.
• W2023474682 hasAuthorship W2023474682A5035095307 @default.
• W2023474682 hasAuthorship W2023474682A5038574644 @default.
• W2023474682 hasAuthorship W2023474682A5054423486 @default.
• W2023474682 hasAuthorship W2023474682A5058205892 @default.
• W2023474682 hasAuthorship W2023474682A5060105528 @default.
• W2023474682 hasAuthorship W2023474682A5075729521 @default.
• W2023474682 hasAuthorship W2023474682A5080707052 @default.
• W2023474682 hasBestOaLocation W20234746821 @default.
• W2023474682 hasConcept C100701293 @default.
• W2023474682 hasConcept C104317684 @default.
• W2023474682 hasConcept C105795698 @default.
• W2023474682 hasConcept C129848803 @default.
• W2023474682 hasConcept C135763542 @default.
• W2023474682 hasConcept C137132547 @default.
• W2023474682 hasConcept C137403100 @default.
• W2023474682 hasConcept C144024400 @default.
• W2023474682 hasConcept C149923435 @default.
• W2023474682 hasConcept C153209595 @default.
• W2023474682 hasConcept C166976648 @default.
• W2023474682 hasConcept C186413461 @default.
• W2023474682 hasConcept C19165224 @default.

• next