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- W2023484895 abstract "Abstract Observations with the electron microscope were made on sections of leaves of the M 5 generation of Ageratum plants whose ancestral seeds had been incubated for 18 hr in 0.01 M 5-bromodeoxyuridine. Severe defects in chloroplast structure were observed in some cells, while in other cells the chloroplasts appeared normal. Within a single cell a variety of degrees of imperfection in chloroplast structure was present. The electron microscopic picture could be correlated with the finding of chlorophyll-deficient mottling of leaves in the descendants of the 5-bromodeoxyuridine treated seeds. These lesions were not observed in control plants. It appears that 5-bromodeoxyuridine has induced mutations in the genetic machinery involved in chloroplast development. Thus in a higher plant transition of bases and possibly other alterations in the DNA molecule set off a chain of events which, in subsequent generations, results in persistent damage to steps involved in construction of chloroplasts." @default.
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- W2023484895 date "1967-01-01" @default.
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- W2023484895 title "Mutation of chloroplasts in ageratum, following treatment with 5-bromodeoxyuridine" @default.
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- W2023484895 doi "https://doi.org/10.1016/0014-4827(67)90125-5" @default.
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