FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W202348765> ?p ?o ?g. }

• W202348765 endingPage "113" @default.
• W202348765 startingPage "99" @default.
• W202348765 abstract "Mucopolysaccharidosis (MPS) II, or Hunter syndrome, is a lysosomal storage disease characterized by multi-systemic involvement and a progressive clinical course. Enzyme replacement therapy with idursulfase has been approved in more than 50 countries worldwide; however, safety and efficacy data from clinical studies are currently only available for patients 1.4 years of age and older. Sibling case studies of infants with MPS I, II, and VI who initiated ERT in the first weeks or months of life have reported no new safety concerns and a more favorable clinical course for the sibling treated in infancy than for the later-treated sibling. Here we describe our experiences with a case series of eight MPS II patients for whom idursulfase treatment was initiated at under 1 year of age. The majority of the patients were diagnosed because of a family history of disease. All of the infants displayed abnormalities consistent with MPS II at diagnosis. The youngest age at treatment start was 10 days and the oldest was 6.5 months, with duration of treatment varying between 6 weeks and 5.5 years. No new safety concerns were observed, and none of the patients experienced an infusion-related reaction. All of the patients treated for more than 6 weeks showed improvements and/or stabilization of some somatic manifestations while on treatment. In some cases, caregivers made comparisons with other affected family members and reported that the early-treated patients experienced a less severe clinical course, although a lack of medical records for many family members precluded a rigorous comparison." @default.
• W202348765 created "2016-06-24" @default.
• W202348765 creator A5002597500 @default.
• W202348765 creator A5011620244 @default.
• W202348765 creator A5013708747 @default.
• W202348765 creator A5021244841 @default.
• W202348765 creator A5031505605 @default.
• W202348765 creator A5052457907 @default.
• W202348765 creator A5059065392 @default.
• W202348765 creator A5074869867 @default.
• W202348765 creator A5078699353 @default.
• W202348765 creator A5079080628 @default.
• W202348765 creator A5085315279 @default.
• W202348765 creator A5089564343 @default.
• W202348765 date "2014-01-01" @default.
• W202348765 modified "2023-10-01" @default.
• W202348765 title "Enzyme Replacement Therapy in Mucopolysaccharidosis II Patients Under 1 Year of Age" @default.
• W202348765 cites W1545744192 @default.
• W202348765 cites W1977499972 @default.
• W202348765 cites W1989295722 @default.
• W202348765 cites W1993027304 @default.
• W202348765 cites W2000685247 @default.
• W202348765 cites W2012973972 @default.
• W202348765 cites W2018988046 @default.
• W202348765 cites W2027292988 @default.
• W202348765 cites W2034511507 @default.
• W202348765 cites W2041954226 @default.
• W202348765 cites W2042067606 @default.
• W202348765 cites W2044026349 @default.
• W202348765 cites W2049736899 @default.
• W202348765 cites W2065001163 @default.
• W202348765 cites W2070868153 @default.
• W202348765 cites W2092327321 @default.
• W202348765 cites W2092848229 @default.
• W202348765 cites W2108681631 @default.
• W202348765 cites W2117030035 @default.
• W202348765 cites W2134289846 @default.
• W202348765 cites W2148584888 @default.
• W202348765 cites W2156621878 @default.
• W202348765 cites W2158683180 @default.
• W202348765 cites W2159466305 @default.
• W202348765 doi "https://doi.org/10.1007/8904_2013_289" @default.
• W202348765 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4213327" @default.
• W202348765 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/24515576" @default.
• W202348765 hasPublicationYear "2014" @default.
• W202348765 type Work @default.
• W202348765 sameAs 202348765 @default.
• W202348765 citedByCount "38" @default.
• W202348765 countsByYear W2023487652014 @default.
• W202348765 countsByYear W2023487652015 @default.
• W202348765 countsByYear W2023487652016 @default.
• W202348765 countsByYear W2023487652017 @default.
• W202348765 countsByYear W2023487652018 @default.
• W202348765 countsByYear W2023487652019 @default.
• W202348765 countsByYear W2023487652020 @default.
• W202348765 countsByYear W2023487652021 @default.
• W202348765 countsByYear W2023487652022 @default.
• W202348765 countsByYear W2023487652023 @default.
• W202348765 crossrefType "book-chapter" @default.
• W202348765 hasAuthorship W202348765A5002597500 @default.
• W202348765 hasAuthorship W202348765A5011620244 @default.
• W202348765 hasAuthorship W202348765A5013708747 @default.
• W202348765 hasAuthorship W202348765A5021244841 @default.
• W202348765 hasAuthorship W202348765A5031505605 @default.
• W202348765 hasAuthorship W202348765A5052457907 @default.
• W202348765 hasAuthorship W202348765A5059065392 @default.
• W202348765 hasAuthorship W202348765A5074869867 @default.
• W202348765 hasAuthorship W202348765A5078699353 @default.
• W202348765 hasAuthorship W202348765A5079080628 @default.
• W202348765 hasAuthorship W202348765A5085315279 @default.
• W202348765 hasAuthorship W202348765A5089564343 @default.
• W202348765 hasBestOaLocation W2023487652 @default.
• W202348765 hasConcept C126322002 @default.
• W202348765 hasConcept C138496976 @default.
• W202348765 hasConcept C141071460 @default.
• W202348765 hasConcept C15744967 @default.
• W202348765 hasConcept C187212893 @default.
• W202348765 hasConcept C195910791 @default.
• W202348765 hasConcept C2776194465 @default.
• W202348765 hasConcept C2776225084 @default.
• W202348765 hasConcept C2779134260 @default.
• W202348765 hasConcept C2779416428 @default.
• W202348765 hasConcept C2779969927 @default.
• W202348765 hasConcept C2910638406 @default.
• W202348765 hasConcept C71924100 @default.
• W202348765 hasConceptScore W202348765C126322002 @default.
• W202348765 hasConceptScore W202348765C138496976 @default.
• W202348765 hasConceptScore W202348765C141071460 @default.
• W202348765 hasConceptScore W202348765C15744967 @default.
• W202348765 hasConceptScore W202348765C187212893 @default.
• W202348765 hasConceptScore W202348765C195910791 @default.
• W202348765 hasConceptScore W202348765C2776194465 @default.
• W202348765 hasConceptScore W202348765C2776225084 @default.
• W202348765 hasConceptScore W202348765C2779134260 @default.
• W202348765 hasConceptScore W202348765C2779416428 @default.
• W202348765 hasConceptScore W202348765C2779969927 @default.
• W202348765 hasConceptScore W202348765C2910638406 @default.
• W202348765 hasConceptScore W202348765C71924100 @default.

• next