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- W2023492892 abstract "Abstract Objective To evaluate the safety and efficacy of vaginal misoprostol for second‐trimester abortion in women with 3 or more prior cesarean deliveries. Methods This study was conducted with 138 women who needed pregnancy termination between 13 and 26 gestational weeks, 31 with 3 or more previous cesarean deliveries and 107 with no uterine scars (the controls). Misoprostol was inserted in the vagina every 6 hours until regular contractions or products of conception appeared, a 200‐µg tablet for the first 24 hours and 2 tablets thereafter. The outcomes assessed were successful vaginal abortion, hemorrhage requiring blood transfusion, incomplete abortion, and uterine rupture. Results A vaginal abortion occurred in 28 women (90.3%) in the study group and 107 (100%) in the control group ( P = 0.01). There were no significant differences in the prevalence of the other assessed outcomes. Conclusion Vaginal misoprostol appears to be safe and acceptably effective for second‐trimester pregnancy termination in women with 3 or more previous cesarean deliveries." @default.
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- W2023492892 date "2010-04-02" @default.
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- W2023492892 title "Midtrimester abortion using vaginal misoprostol for women with three or more prior cesarean deliveries" @default.
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- W2023492892 doi "https://doi.org/10.1016/j.ijgo.2010.02.008" @default.
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