FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2023495104> ?p ?o ?g. }

• W2023495104 endingPage "440" @default.
• W2023495104 startingPage "433" @default.
• W2023495104 abstract "Each year, millions of prescriptions are written for antiarrhythmic drug suppression of ventricular arrhythmias. A large portion of these prescriptions are written for patients with asymptomatic, complex ventricular arrhythmias and organic heart disease, termed potentially malignant or potentially lethal. Since arrhythmia suppression in this population is of unproven benefit, we performed the following study: A total of 246 patients (42% with significant left ventricular dysfunction) had complex ventricular arrhythmias, and were treated with one of eight antiarrhythmic drugs (Vaughan Williams classes IA, IB, IC, II, and III). The extent of arrhythmia suppression and the development of serious complications resulting from therapy after 2 weeks was of primary interest. A total of 82 of 246 (33%) maintained adequate (protocol definition) suppression of both ventricular premature beats (VPBs) as well as nonsustained ventricular tachycardia (VT) for 2 weeks, mostly in patients with left ventricular ejection fraction (LVEF) greater than or equal to 40% (p = 0.04 versus LVEF less than 40%). Life-threatening complications of antiarrhythmic therapy occurred most frequently in the 61 patients with an LVEF less than 30% compared to the 185 patients with LVEF greater than or equal to 30% (15% versus 2.1%, p = 0.0005). Suppression of VT was achieved nearly twice as commonly in patients with an LVEF greater than or equal to 30% than in those with an LVEF less than 30% (67% versus 36%; p = 0.0008). Life-threatening complications occurred seven times as frequently in patients presenting with nonsustained VT and an LVEF less than 30% (18% versus 2.3%; p = 0.003).(ABSTRACT TRUNCATED AT 250 WORDS)" @default.
• W2023495104 created "2016-06-24" @default.
• W2023495104 creator A5006688566 @default.
• W2023495104 creator A5028006402 @default.
• W2023495104 creator A5031026816 @default.
• W2023495104 creator A5035785777 @default.
• W2023495104 creator A5055187073 @default.
• W2023495104 creator A5075182651 @default.
• W2023495104 creator A5083179513 @default.
• W2023495104 date "1989-09-01" @default.
• W2023495104 modified "2023-10-17" @default.
• W2023495104 title "The inverse relationship between baseline left ventricular ejection fraction and outcome of antiarrhythmic therapy: A dangerous imbalance in the risk-benefit ratio" @default.
• W2023495104 cites W1966774249 @default.
• W2023495104 cites W1966903368 @default.
• W2023495104 cites W1972279034 @default.
• W2023495104 cites W1973961554 @default.
• W2023495104 cites W1976398721 @default.
• W2023495104 cites W1985961672 @default.
• W2023495104 cites W1999104164 @default.
• W2023495104 cites W1999119637 @default.
• W2023495104 cites W1999710905 @default.
• W2023495104 cites W2006565016 @default.
• W2023495104 cites W2011476261 @default.
• W2023495104 cites W2014562798 @default.
• W2023495104 cites W2017817450 @default.
• W2023495104 cites W2019847201 @default.
• W2023495104 cites W2022307479 @default.
• W2023495104 cites W2025348821 @default.
• W2023495104 cites W2028201641 @default.
• W2023495104 cites W2031745738 @default.
• W2023495104 cites W2035105123 @default.
• W2023495104 cites W2044972611 @default.
• W2023495104 cites W2048422635 @default.
• W2023495104 cites W2051960725 @default.
• W2023495104 cites W2090810169 @default.
• W2023495104 cites W2091235401 @default.
• W2023495104 cites W2094892482 @default.
• W2023495104 cites W2100069431 @default.
• W2023495104 cites W2105897750 @default.
• W2023495104 cites W2110306294 @default.
• W2023495104 cites W2159418569 @default.
• W2023495104 cites W2323345863 @default.
• W2023495104 cites W2337679965 @default.
• W2023495104 cites W2340830615 @default.
• W2023495104 cites W4235788903 @default.
• W2023495104 cites W4239111797 @default.
• W2023495104 cites W4244341064 @default.
• W2023495104 doi "https://doi.org/10.1016/0002-8703(89)90254-8" @default.
• W2023495104 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/2476016" @default.
• W2023495104 hasPublicationYear "1989" @default.
• W2023495104 type Work @default.
• W2023495104 sameAs 2023495104 @default.
• W2023495104 citedByCount "113" @default.
• W2023495104 countsByYear W20234951042012 @default.
• W2023495104 countsByYear W20234951042013 @default.
• W2023495104 countsByYear W20234951042018 @default.
• W2023495104 crossrefType "journal-article" @default.
• W2023495104 hasAuthorship W2023495104A5006688566 @default.
• W2023495104 hasAuthorship W2023495104A5028006402 @default.
• W2023495104 hasAuthorship W2023495104A5031026816 @default.
• W2023495104 hasAuthorship W2023495104A5035785777 @default.
• W2023495104 hasAuthorship W2023495104A5055187073 @default.
• W2023495104 hasAuthorship W2023495104A5075182651 @default.
• W2023495104 hasAuthorship W2023495104A5083179513 @default.
• W2023495104 hasConcept C126322002 @default.
• W2023495104 hasConcept C164705383 @default.
• W2023495104 hasConcept C2776331378 @default.
• W2023495104 hasConcept C2777910003 @default.
• W2023495104 hasConcept C2778198053 @default.
• W2023495104 hasConcept C2908647359 @default.
• W2023495104 hasConcept C71924100 @default.
• W2023495104 hasConcept C78085059 @default.
• W2023495104 hasConcept C99454951 @default.
• W2023495104 hasConceptScore W2023495104C126322002 @default.
• W2023495104 hasConceptScore W2023495104C164705383 @default.
• W2023495104 hasConceptScore W2023495104C2776331378 @default.
• W2023495104 hasConceptScore W2023495104C2777910003 @default.
• W2023495104 hasConceptScore W2023495104C2778198053 @default.
• W2023495104 hasConceptScore W2023495104C2908647359 @default.
• W2023495104 hasConceptScore W2023495104C71924100 @default.
• W2023495104 hasConceptScore W2023495104C78085059 @default.
• W2023495104 hasConceptScore W2023495104C99454951 @default.
• W2023495104 hasIssue "3" @default.
• W2023495104 hasLocation W20234951041 @default.
• W2023495104 hasLocation W20234951042 @default.
• W2023495104 hasOpenAccess W2023495104 @default.
• W2023495104 hasPrimaryLocation W20234951041 @default.
• W2023495104 hasRelatedWork W1996180002 @default.
• W2023495104 hasRelatedWork W2051712573 @default.
• W2023495104 hasRelatedWork W2077083067 @default.
• W2023495104 hasRelatedWork W2091139515 @default.
• W2023495104 hasRelatedWork W2319805938 @default.
• W2023495104 hasRelatedWork W2355594703 @default.
• W2023495104 hasRelatedWork W2361407492 @default.
• W2023495104 hasRelatedWork W3033076790 @default.
• W2023495104 hasRelatedWork W3155674270 @default.
• W2023495104 hasRelatedWork W3187572025 @default.
• W2023495104 hasVolume "118" @default.

• next